CAS 4651-67-6: 7-Ketolithocholic acid
Description:7-Ketolithocholic acid is a bile acid derivative that plays a role in the metabolism of lipids and the regulation of cholesterol levels in the body. It is characterized by its ketone functional group at the C7 position of the steroid nucleus, which distinguishes it from other bile acids. This compound is typically found in the bile of certain animals and is involved in the emulsification of dietary fats, facilitating their absorption in the intestines. Its structure includes a hydrophobic steroid backbone, which contributes to its amphipathic nature, allowing it to interact with both lipids and water. 7-Ketolithocholic acid may also exhibit biological activities, including potential effects on lipid metabolism and gut microbiota. As a bile acid, it is subject to enterohepatic circulation, influencing its concentration and activity in the gastrointestinal tract. Understanding its properties and functions is important for research in gastrointestinal health and metabolic disorders.
Formula:C24H38O4
InChI:InChI=1S/C24H38O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-19,22,25H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,22+,23+,24-/m1/s1
InChI key:InChIKey=DXOCDBGWDZAYRQ-AURDAFMXSA-N
SMILES:O=C(O)CCC(C)C1CCC2C3C(=O)CC4CC(O)CCC4(C)C3CCC12C
- Synonyms:
- (3Alpha,5Beta)-3-Hydroxy-7-Oxocholan-24-Oic Acid
- (3Alpha,5Beta,8Xi,9Xi,10Xi,13Xi,14Xi,17Xi,20Xi)-3-Hydroxy-7-Oxocholan-24-Oic Acid
- (3α,5β)-3-Hydroxy-7-oxo-Cholan-24-oic acid
- (3α,5β)-3-Hydroxy-7-oxocholan-24-oic acid
- 3-Hydroxy-7-Oxocholan-24-Oic Acid
- 3Alpha-Hydroxy-7-Oxo-5Beta-Cholanic Acid
- 3alpha-Hydroxy-7-oxo-5-cholanic acid
- 3alpha-Hydroxy-7-oxo-5beta-cholic acid
- 3α-Hydroxy-7-keto-5β-cholan-24-oic acid
- 3α-Hydroxy-7-keto-5β-cholanic acid
- See more synonyms
- 3α-Hydroxy-7-oxo-5β-cholan-24-oic acid
- 3α-Hydroxy-7-oxo-5β-cholan-24-oicacid
- 3α-Hydroxy-7-oxo-5β-cholanic acid
- 3α-Hydroxy-7-oxo-5β-cholanoic acid
- 3α-Hydroxy-7-oxo-5β-cholic acid
- 5β-Cholan-24-oic acid, 3α-hydroxy-7-oxo-
- 5β-Cholanic acid, 3α-hydroxy-7-oxo-
- 5β-Cholanic acid-3α-ol-7-one
- 7-Ketochenodeoxycholic acid
- 7-Ketolithocholic acid
- 7-Oxo-3α-hydroxycholan-24-oic acid
- 7-Oxolithocholic acid
- 7-keto-Lithocholic acid
- 7K-Lca
- Cholan-24-oic acid, 3-hydroxy-7-oxo-, (3α,5β)-
- Hydroxycholanicacid
- NSC 226118
- Nutriacholic acid
- Obeticholic Acid Intermediate
- keto-Lithocholic acid
