CAS 4651-97-2

2-amino-4-methylthiophene-3-carboxamide

Description:

2-Amino-4-methylthiophene-3-carboxamide is an organic compound characterized by its thiophene ring structure, which is a five-membered aromatic ring containing sulfur. This compound features an amino group (-NH2) and a carboxamide group (-C(=O)NH2) attached to the thiophene ring, contributing to its polar nature and potential for hydrogen bonding. The presence of a methyl group at the 4-position of the thiophene enhances its hydrophobic characteristics. This compound is typically solid at room temperature and may exhibit solubility in polar solvents due to its functional groups. It is of interest in various fields, including pharmaceuticals and materials science, due to its potential biological activity and utility in synthesizing other chemical entities. The compound's reactivity can be influenced by the functional groups present, making it a candidate for further chemical modifications. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₆H₈N₂OS

InChI: InChI=1/C6H8N2OS/c1-3-2-10-6(8)4(3)5(7)9/h2H,8H2,1H3,(H2,7,9)

SMILES: Cc1csc(c1C(=O)N)N

2-Amino-4-methylthiophene-3-carboxamide, 98%

CAS: 4651-97-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₈N₂OS

Purity: 98%

Color and Shape: White to cream or pale yellow, Crystals or powder or crystalline powder

Molecular weight: 156.20

Ref: 02-B20043

2-Amino-4-methylthiophene-3-carboxamide

CAS: 4651-97-2

Formula: C₆H₈N₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 156.2055

Ref: IN-DA003GFN

2-Amino-4-methylthiophene-3-carboxamide

CAS: 4651-97-2

2-Amino-4-methylthiophene-3-carboxamide

Purity: 95%

Molecular weight: 156.20551g/mol

Ref: 54-OR24237

2-Amino-4-methylthiophene-3-carboxamide

CAS: 4651-97-2

2-Amino-4-methylthiophene-3-carboxamide is a small molecule that is a potent inhibitor of the JAK2 kinase. This enzyme is associated with human fibrosis and has been shown to be involved in the development of liver fibrosis in rats. 2-Amino-4-methylthiophene-3-carboxamide inhibits the production of cytokines such as IL1α, IL6, and TNFα. It also blocks the activation of transcription factors such as NFκB, which are involved in inflammation. The compound has been shown to be orally active and has demonstrated efficacy in animal studies. Analogues have also been synthesized for this compound that show similar activity.

Formula: C₆H₈N₂OS

Purity: (%) Min. 85%

Color and Shape: Powder

Molecular weight: 156.21 g/mol

Ref: 3D-FA157546

2-Amino-4-methyl-3-thiophene carboxamide

CAS: 4651-97-2

Formula: C₆H₈N₂OS

Purity: 98.0%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 156.2

Ref: 10-F024813