CAS 466-07-9
:neriifolin
Description:
Neriifolin, with the CAS number 466-07-9, is a naturally occurring compound classified as a glycoside. It is primarily derived from the plant Nerium oleander, commonly known as oleander. Neriifolin exhibits a range of biological activities, including potential anti-inflammatory and cytotoxic effects, which have garnered interest in pharmacological research. The compound is characterized by its glycosidic structure, which typically consists of a sugar moiety linked to a non-sugar aglycone. This structural feature is significant as it influences the compound's solubility, stability, and biological interactions. Neriifolin is known to interact with various biological pathways, making it a subject of study for its therapeutic potential. However, it is important to note that oleander and its derivatives can be toxic, and caution is advised when considering their use. Overall, neriifolin represents a fascinating area of study within natural products chemistry, with implications for drug development and understanding plant-based medicinal compounds.
Formula:C30H46O8
InChI:InChI=1/C30H46O8/c1-16-24(32)26(35-4)25(33)27(37-16)38-19-7-10-28(2)18(14-19)5-6-22-21(28)8-11-29(3)20(9-12-30(22,29)34)17-13-23(31)36-15-17/h13,16,18-22,24-27,32-34H,5-12,14-15H2,1-4H3/t16?,18-,19-,20-,21?,22?,24-,25?,26?,27+,28+,29-,30+/m1/s1
InChI key:InChIKey=VPUNMTHWNSJUOG-BAOINKAISA-N
SMILES:O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5[C@@H](O)[C@H](OC)[C@@H](O)[C@H](C)O5)CC4)[H])(CC[C@]1(C)[C@H](CC2)C6=CC(=O)OC6)[H])[H]
Synonyms:- (3-beta,5-beta)-3-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (3alpha,5beta,8xi,9xi)-3-[(6-deoxy-3-O-methyl-beta-D-glycero-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (3beta,5beta)-3-[(6-deoxy-3-O-methylhexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (3beta,5beta,8xi,9xi)-3-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (3beta,5beta,8xi,9xi,17xi)-3-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (3β,5β)-3-[(6-Deoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- 17β-Neriifolin
- Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-
- NSC 123976
- Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-
- Neriifolin
- (3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (17R)-3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14-hydroxy-5β,14β-carda-20(22)-enolide
- 3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14β-hydroxy-5β-carda-20(22)-enolide
- 14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside), 3-([6-Deoxy-3-O-methyl-α-L-glucopyranosyl]oxy)-14-hydroxy-5β-card-20(22)-enolide]
- xy)-14-hydroxy-
- 3β-[(3-O-Methyl-6-deoxy-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide
- 14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside)
- NERIIFOLIN USP/EP/BP
- 3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide
- (5beta)-3beta-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- digitoxigenin+thevetose
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Found 6 products.
Neriifolin
CAS:Neriifolin (17β-Neriifolin), a cardiac glycoside extracted from the unripe fruits of Cerbera manghas, is a Na+K+-ATPase inhibitor with anticancer activity.Formula:C30H46O8Color and Shape:SolidMolecular weight:534.6817β-Neriifolin
CAS:<p>Applications 17β-neriifolin could be considered a candidate for the treatment of hepatocellular carcinoma. It can also work as an inhibitor of hERG channel trafficking.<br>References Zhao, Q., et al.:Fitoterapia, 82, 735 (2011); Wang, L., et al.: J. Pharmacol. Exper. Ther., 320, 525 (2007)<br></p>Formula:C30H46O8Color and Shape:NeatMolecular weight:534.68Neriifolin
CAS:Neriifolin is a potent anticancer compound that has been isolated from the Chinese plant, Nerium oleander. It belongs to the class of xylan analogs and has been shown to inhibit the growth of cancer cells by inducing apoptosis. Neriifolin targets the cell cycle and inhibits the activity of protein kinases, which are essential for cell division. It has demonstrated significant inhibitory effects on tumor growth in human cancer cell lines, making it a promising candidate for cancer therapy. In addition, Neriifolin has been found to be a potent inhibitor of several key enzymes involved in cancer progression, making it an attractive target for developing new cancer therapies. Its effectiveness as an anticancer agent makes Neriifolin an important tool in the fight against cancer.Formula:C30H46O8Purity:Min. 95%Molecular weight:534.7 g/mol





