CAS 467-55-0

hecogenin

Description:

Hecogenin is a naturally occurring steroid sapogenin derived from various plant sources, particularly from the genus Agave. It is characterized by its molecular structure, which includes a steroid backbone with specific functional groups that contribute to its biological activity. Hecogenin is a white to off-white crystalline powder that is insoluble in water but soluble in organic solvents such as ethanol and chloroform. Its chemical formula is C27H44O3, and it has a molecular weight of approximately 416.65 g/mol. Hecogenin is known for its potential pharmacological properties, including anti-inflammatory and anti-cancer activities, making it of interest in medicinal chemistry and pharmaceutical research. Additionally, it serves as a precursor in the synthesis of various steroid hormones and other bioactive compounds. Due to its natural origin and biological significance, hecogenin is studied for its applications in traditional medicine and modern therapeutic formulations.

Formula: C₂₇H₄₂O₄

InChI: InChI=1/C27H42O4/c1-15-7-10-27(30-14-15)16(2)24-22(31-27)12-21-19-6-5-17-11-18(28)8-9-25(17,3)20(19)13-23(29)26(21,24)4/h15-22,24,28H,5-14H2,1-4H3/t15?,16-,17-,18-,19+,20-,21-,22-,24-,25-,26+,27?/m0/s1

InChI key: InChIKey=QOLRLLFJMZLYQJ-LOBDNJQFSA-N

SMILES: C[C@@]12[C@@]3([C@](C[C@]1([C@]4([C@](CC2=O)([C@]5(C)[C@@](CC4)(C[C@@H](O)CC5)[H])[H])[H])[H])(O[C@@]6([C@H]3C)CC[C@@H](C)CO6)[H])[H]

Synonyms:

• (25R)-3b-Hydroxy-5a-spirostan-12-one
• (3Beta,5Alpha,22Xi)-3-Hydroxyspirostan-12-One
• (3Beta,5Alpha,8Xi,9Xi,14Xi,16Xi,17Xi,20Xi,22Xi)-3-Hydroxyspirostan-12-One
• (3beta,5alpha,25R)-3-hydroxyspirostan-12-one
• (3β,5α,25R)-3-Hydroxyspirostan-12-one
• 12-Oxotigogenin
• 25(R)-3β-Hydroxyspirostan-12-one
• 3-Beta-Hydroxy-5-Alpha-Spirostan-12-One
• 3-Hydroxyspirostan-12-One
• 3beta-Hydroxy-5alpha-spirostan-12-one
• 3β-Hydroxy-5α-hecogenin
• 5α,25<span class="text-smallcaps">D</span>-Spirostan-12-one, 3β-hydroxy-
• 5α-Spirostan-12-one, 3β-hydroxy-, (25R)-
• Gekogenin
• Hekogenin
• Hocogenin
• NSC 115921
• Spirostan-12-one, 3-hydroxy-, (3β,5α,25R)-
• Hecogenin
• 5α,25D-Spirostan-12-one, 3β-hydroxy-
• 5-ALPHA, 20-ALPHA, 22-ALPHA, 25D-SPIROSTAN-3-BETA-OL-12-ONE
• HECOGENIN 98.0% BY HPLC
• (25R)-5-Spirostan-3-ol-12-one
• (3,5,25R)-3-Hydroxysiprostan-12-one
• 3β-Hydroxy-5α-spirostan-12-one, 5α-Spirostan-3β-ol-12-one
• (3,5,25R)-3-Hydroxysiprostan-1
• 3-b-Hydroxy-5-a-spirostan-12-one
• HECOGENIN (3B-HYDROXY-5A-SPIROSTAN-12-ONE)
• 25R,5ALPHA-SPIROSTAN-3BETA-OL-12-ONE
• Hecoginin

Hecogenin

CAS: 467-55-0

Formula: C₂₇H₄₂O₄

Purity: >80.0%(GC)

Color and Shape: White to Light yellow to Light red powder to crystal

Molecular weight: 430.63

Ref: 3B-H0003

Hecogenin

CAS: 467-55-0

Formula: C₂₇H₄₂O₄

Purity: 80%

Color and Shape: Solid

Molecular weight: 430.6200

Ref: IN-DA003QUC

Hecogenin

CAS: 467-55-0

Hecogenin

Purity: ≥98%

Molecular weight: 430.62g/mol

Ref: 54-BUP11301

Hecogenin

CAS: 467-55-0

Formula: C₂₇H₄₂O₄

Molecular weight: 430.63

Ref: 7W-GY4752

Hecogenin

CAS: 467-55-0

Formula: C₂₇H₄₂O₄

Purity: 95%~99%

Molecular weight: 430.629

Ref: BP-BP0705

Hecogenin

CAS: 467-55-0

Hecogenin (Hocogenin), a steroid saponin derived from Agave sisalana, serves as a specific inhibitor for human UDP-glucuronosyltransferases.

Formula: C₂₇H₄₂O₄

Purity: 99.38% - 99.82%

Color and Shape: White Solid

Molecular weight: 430.62

Ref: TM-T4878

Hecogenin

CAS: 467-55-0

Oxygen-heterocyclic compound

Formula: C₂₇H₄₂O₄

Purity: ≥ 90.0 % (GC)

Color and Shape: Powder

Molecular weight: 430.63

Ref: 5G-83508

Hecogenin (>80%)

Controlled Product

CAS: 467-55-0

Applications Hecogenin, is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.
References Gama, K. B., et al.: J. Natural Prod., 76, 559 (2013);

Formula: C₂₇H₄₂O₄

Purity: >80%

Color and Shape: Neat

Molecular weight: 430.62

Ref: TR-H129945

Hecogenin

CAS: 467-55-0

Hecogenin is a steroidal sapogenin, which is derived from the agave plant. As a naturally occurring compound, it is obtained through the hydrolytic processing of saponins present in specific agave species. The mode of action of hecogenin involves serving as a critical precursor in the synthesis of steroidal drugs, particularly corticosteroids and anabolic steroids. This capability arises from its structural similarity to steroid molecules, allowing it to be enzymatically converted into various pharmaceutical agents.

Formula: C₂₇H₄₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 430.62 g/mol

Ref: 3D-FH73900