CAS 467-77-6

(-)-Coronaridine

Description:

(-)-Coronaridine is a naturally occurring alkaloid primarily derived from the plant species of the Apocynaceae family, particularly from the genus Tabernaemontana. It is characterized by its complex indole structure, which contributes to its biological activity. The compound exhibits a range of pharmacological properties, including potential analgesic and anti-inflammatory effects, making it of interest in medicinal chemistry. (-)-Coronaridine has been studied for its interactions with various neurotransmitter systems, particularly in relation to the central nervous system. Its stereochemistry is significant, as the (-) enantiomer is often associated with specific biological activities. The substance is typically encountered as a white to off-white crystalline solid and is soluble in organic solvents. Due to its bioactive nature, (-)-Coronaridine is also being investigated for its potential therapeutic applications, although further research is needed to fully elucidate its mechanisms of action and efficacy in clinical settings. As with many alkaloids, safety and toxicity profiles are important considerations in its study and application.

Formula: C₂₁H₂₆N₂O₂

InChI: InChI=1S/C21H26N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,13-14,19,22H,3,8-12H2,1-2H3/t13-,14+,19+,21-/m1/s1

InChI key: InChIKey=NVVDQMVGALBDGE-PZXGUROGSA-N

SMILES: C(OC)(=O)[C@]12[C@]3([N@](C[C@@](C1)(C[C@@H]3CC)[H])CCC4=C2NC=5C4=CC=CC5)[H]

Synonyms:

• (-)-Coronaridine
• 6,9-Methano-5H-pyrido[1′,2′:1,2]azepino[4,5-b]indole, ibogamine-18-carboxylic acid deriv.
• Coronardine
• Coronaridin
• Ibogamine-18-carboxylic acid, methyl ester
• Methyl (2Alpha)-Ibogamine-18-Carboxylate
• Methyl 19-Hydroxyibogamine-18-Carboxylate Hydrochloride (1:1)
• Nsc 127490
• Methyl ibogamine-18-carboxylate

methyl ibogamine-18-carboxylate

CAS: 467-77-6

Formula: C₂₁H₂₆N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 338.4433

Ref: IN-DA00DLQ8

Coronaridine

CAS: 467-77-6

Coronaridine is a useful organic compound for research related to life sciences. The catalog number is T124824 and the CAS number is 467-77-6.

Formula: C₂₁H₂₆N₂O₂

Color and Shape: Solid

Molecular weight: 338.451

Ref: TM-T124824

Ibogamine-18-carboxylic acid methyl ester

CAS: 467-77-6

Ibogamine is a naturally occurring alkaloid that is found in the roots of plants from the Apocynaceae family. It has been shown to be low-potency and act as an α7 nicotinic acetylcholine receptor agonist. Ibogamine also possesses transport properties through the blood-brain barrier. In addition, it has been shown to inhibit coronaridine-induced convulsions in mice and alkaloids have been isolated from its leaves. Molecular docking analysis has shown that ibogamine binds to the protein data of hep-2 cells, which are used for tissue culture. Ibogamine is a monoterpenoid indole alkaloid with anti-inflammatory properties. It has been shown to have activity against infectious diseases such as tissue culture and plate test experiments, which are used to study fatty acid synthesis and β-oxidation respectively.

Formula: C₂₁H₂₆N₂O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 338.44 g/mol

Ref: 3D-FI157133

Ibogamine-18-carboxylic Acid Methyl Ester

Controlled Product

CAS: 467-77-6

Formula: C₂₁H₂₆N₂O₂

Color and Shape: Neat

Molecular weight: 338.443

Ref: TR-I249775

Coronaridine

CAS: 467-77-6

Formula: C₂₁H₂₆N₂O₂

Molecular weight: 338.44

Ref: ST-EA-CP-C508001