CAS: 467214-20-6 - Alvespimycin

Formula: C₃₂H₄₈N₄O₈

InChI: InChI=1S/C32H48N4O8/c1-18-14-22-27(34-12-13-36(5)6)24(37)17-23(29(22)39)35-31(40)19(2)10-9-11-25(42-7)30(44-32(33)41)21(4)16-20(3)28(38)26(15-18)43-8/h9-11,16-18,20,25-26,28,30,34,38H,12-15H2,1-8H3,(H2,33,41)(H,35,40)/b11-9-,19-10+,21-16+/t18-,20+,25+,26+,28-,30+/m1/s1

InChI key: InChIKey=KUFRQPKVAWMTJO-LMZWQJSESA-N

SMILES: O=C(OC1C(=CC(C)C(O)C(OC)CC(C)CC=2C(=O)C(=CC(=O)C2NCCN(C)C)NC(=O)C(=CC=CC1OC)C)C)N

Synonyms:

• 17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin
• 17-Dimethylaminoethylamino-17-demethoxygeldanamycin
• 17-Dmag
• 17-N-(2-Dimethylaminoethylamino)-17-demethoxygeldanamycin
• 17-[2-(Dimethylamino)ethylamino]-17-desmethylgeldanamycin
• Geldanamycin, 17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-
• NSC 707545

17-DMAG

CAS: 467214-20-6

• Formula: C₃₂H₄₈N₄O₈
• Purity: 100%
• Color and Shape: Solid
• Molecular weight: 616.7455

Alvespimycin

CAS: 467214-20-6

Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding …

• Formula: C₃₂H₄₈N₄O₈
• Purity: 100%
• Color and Shape: Solid
• Molecular weight: 616.75

17-Dimethylaminoethylamino-17-demethoxygeldanamycin

CAS: 467214-20-6

• Color and Shape: Purple Powder
• Molecular weight: 653.21g/mol

Alvespimycin Hydrochloride

CAS: 467214-20-6467214-21-7

• Formula: C₃₂H₄₈N₄O₈·HCl
• Molecular weight: 616.76 36.46

17-Dimethylaminoethylamino-17-demethoxygeldanamycin

CAS: 467214-20-6

• Formula: C₃₂H₄₈N₄O₈
• Purity: ≥ 98.0%
• Color and Shape: Purple to black powder
• Molecular weight: 616.75

Alvespimycin hydrochloride

CAS: 467214-20-6

Alvespimycin hydrochloride is a chemical inhibitor that binds to the ATP-binding site of Hsp90, an …

• Formula: C₃₂H₄₈N₄O₈
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 616.75 g/mol

17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin-d6

CAS: 467214-20-6

• Formula: C₃₂D₆H₄₂N₄O₈
• Color and Shape: Neat
• Molecular weight: 622.783