CAS 468-28-0

Lupulone

Description:

Lupulone is a chemical compound classified as a bitter acid, primarily found in hops (Humulus lupulus), which are used in brewing beer. It is known for its antimicrobial properties and contributes to the flavor and aroma profile of beer. Lupulone has a complex structure, characterized by a long carbon chain and multiple functional groups, including a phenolic ring. This compound exhibits a yellowish to brownish color and is typically insoluble in water but soluble in organic solvents. Its bitterness is a key attribute, influencing the taste of beer and acting as a natural preservative. Additionally, lupulone has been studied for its potential health benefits, including anti-inflammatory and antioxidant effects. The compound's CAS number, 468-28-0, is a unique identifier that facilitates its identification in chemical databases and regulatory frameworks. Overall, lupulone plays a significant role in both the brewing industry and potential therapeutic applications, making it a compound of interest in both food science and pharmacology.

Formula: C₂₆H₃₈O₄

InChI: InChI=1S/C26H38O4/c1-16(2)9-10-20-23(28)22(21(27)15-19(7)8)25(30)26(24(20)29,13-11-17(3)4)14-12-18(5)6/h9,11-12,19,28,30H,10,13-15H2,1-8H3

InChI key: InChIKey=WPVSVIXDXMNGGN-UHFFFAOYSA-N

SMILES: C(C=C(C)C)C1(CC=C(C)C)C(O)=C(C(CC(C)C)=O)C(O)=C(CC=C(C)C)C1=O

Synonyms:

• 2,4-Cyclohexadien-1-one, 3,5-dihydroxy-2,6,6-tris(3-methyl-2-buten-1-yl)-4-(3-methyl-1-oxobutyl)-
• 2,4-Cyclohexadien-1-one, 3,5-dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-
• 3,5-Dihydroxy-2,6,6-tris(3-methyl-2-buten-1-yl)-4-(3-methyl-1-oxobutyl)-2,4-cyclohexadien-1-one
• 3,5-Dihydroxy-2-(3-Methylbutanoyl)-4,6,6-Tris(3-Methylbut-2-En-1-Yl)Cyclohexa-2,4-Dien-1-One
• Lupulon
• Lupulone
• Lupulone β-acid
• n-Lupulone
• β-Lupulic acid

8-oxo-hexadecanoic acid

CAS: 468-28-0

8-oxo-hexadecanoic acid

Purity: ≥95%

Molecular weight: 270.41g/mol

Ref: 54-BUP20406

Lupulone

CAS: 468-28-0

Formula: C₂₆H₃₈O₄

Purity: 95%~99%

Molecular weight: 414.586

Ref: BP-BP0894

Lupulone

CAS: 468-28-0

Formula: C₂₆H₃₈O₄

Molecular weight: 414.59

Ref: 4Z-P-249031

Lupulone (stable dcha salt)

CAS: 468-28-0

Ketone alcohol

Formula: C₂₆H₃₈O₄xC₁₂H₂₃N

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 595.9

Ref: 5G-86708

Lupulone

Controlled Product

CAS: 468-28-0

Stability Hygroscopic
Applications Lupulone is a hop plant (Humulus lupulus L.) acid that inhibits tumorigenicity of hepatocellular carcinoma cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Saugspier, M. et al.: Onc. Rep., 28, 1423 (2012); Kavalier, A. et al.: J. Agri. Food Chem., 59, 4783 (2011);

Formula: C₂₆H₃₈O₄

Color and Shape: White To Light Yellow

Molecular weight: 414.58

Ref: TR-L478000

Lupulone

CAS: 468-28-0

Lupulone is a bitter acid compound that is an essential component of hops (Humulus lupulus), traditionally used in brewing. It originates from the lupulin glands found in cone-like structures of the hop plant. Lupulone's mode of action involves disrupting microbial cell membranes, inhibiting cellular processes in various microorganisms. Additionally, it exhibits potential anti-cancer activities, possibly by inducing apoptosis and inhibiting tumor growth pathways.

Formula: C₂₆H₃₈O₄

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 414.58 g/mol

Ref: 3D-FL74820

Lupulon

CAS: 468-28-0

Lupulon has a role as an apoptosis inducer, antimicrobial agent, angiogenesis inhibitor, and antineoplastic agent.

Formula: C₂₆H₃₈O₄

Color and Shape: Solid

Molecular weight: 414.58

Ref: TM-T21005