CAS 4684-32-6

Picrinine

Description:

Picrinine, with the CAS number 4684-32-6, is an alkaloid derived from the plant Picrorrhiza kurroa, commonly known for its traditional medicinal uses. It is characterized by its complex structure, which includes a bicyclic framework. Picrinine is typically a yellowish crystalline solid and is known for its bitter taste. The compound exhibits various biological activities, including potential anti-inflammatory and antioxidant properties, making it of interest in pharmacological research. It is soluble in organic solvents but has limited solubility in water. Due to its alkaloid nature, picrinine may interact with biological systems, influencing neurotransmitter pathways. However, its use is often limited by its toxicity and potential side effects, necessitating careful handling and further investigation into its safety profile. Overall, picrinine represents a fascinating subject of study within the field of natural products and medicinal chemistry, highlighting the importance of plant-derived compounds in drug discovery.

Formula: C₂₀H₂₂N₂O₃

InChI: InChI=1S/C20H22N2O3/c1-3-11-10-22-15-8-12(11)17(18(23)24-2)19-9-16(22)25-20(15,19)21-14-7-5-4-6-13(14)19/h3-7,12,15-17,21H,8-10H2,1-2H3/b11-3-/t12-,15-,16-,17-,19-,20-/m0/s1

InChI key: InChIKey=BDXYPHKGNUGUFG-VETGLWQVSA-N

SMILES: C(OC)(=O)[C@H]1[C@]23[C@@]4([C@]5(N([C@](C2)(O4)[H])C\C(=C\C)\[C@@]1(C5)[H])[H])NC=6C3=CC=CC6

Synonyms:

• 16-De[(acetyloxy)methyl]picraline
• 2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester, (2R,3E,6S,7aR,12aR,12bS,14R)-
• 2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester, [2R-(2α,3E,6β,7aα,12aβ,12bβ,14R*)]-
• 2H,12H-6,12a-epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester, (2R,3E,6S,7aR,12aR,12bS)-
• 2Α,5Α-Epoxy-1,2-Dihydroakuammilan-17-Oic Acid Methyl Ester
• Akuammilan-17-oic acid, 2,5-epoxy-1,2-dihydro-, methyl ester, (2α,5α)-
• Deacetyldeformopicraline
• Methyl (2alpha,5alpha,15alpha,16xi,19E)-1,2-dihydro-2,5-epoxyakuammilan-17-oate
• Methyl 1,2-Dihydro-2,5-Epoxyakuammilan-17-Oate
• Picraline, deacetyldeformo-
• Picrinine

2α,5α-Epoxy-1,2-dihydroakuammilan-17-oic acid methyl ester

CAS: 4684-32-6

Formula: C₂₀H₂₂N₂O₃

Purity: 95%

Molecular weight: 338.4003

Ref: IN-DA00D7ZK

Picrinine

CAS: 4684-32-6

Picrinine

Purity: ≥98%

Molecular weight: 338.4g/mol

Ref: 54-BUP00865

Picrinine

CAS: 4684-32-6

Picrinine is an akuammiline alkaloid extracted from the leaves of Alstonia scholaris. It exhibits anti-inflammatory activity by inhibiting 5-lipoxygenase.

Formula: C₂₀H₂₂N₂O₃

Purity: 99.96%

Color and Shape: Solid

Molecular weight: 338.40

Ref: TM-TN2068

Picrinine

CAS: 4684-32-6

Formula: C₂₀H₂₂N₂O₃

Purity: 95%~99%

Molecular weight: 338.407

Ref: BP-BP1096

Picrinine

CAS: 4684-32-6

Picrinine is a hydrochloric acid-insoluble alkaloid that can be found in the Apocynaceae family. It has been shown to have synergistic effects with other alkaloids such as apocynin and picrates, which are also present in the plant. Picrinine has been used for the treatment of chronic cough, chronic bronchitis, and cancer. It inhibits cell proliferation by inhibiting protein synthesis and inducing apoptosis. Picrinine is extracted from plants using an LC-MS/MS method and has been shown to inhibit the growth of cancer cells in vitro.

Purity: Min. 95%

Ref: 3D-FP74097