CAS 4684-94-0

6-Chloropicolinic acid

Description:

6-Chloropicolinic acid is an organic compound characterized by its chlorinated pyridine structure. It features a carboxylic acid functional group and a chlorine atom positioned at the 6th carbon of the pyridine ring. This compound is typically a white to off-white crystalline solid, exhibiting moderate solubility in water and higher solubility in organic solvents such as ethanol and acetone. Its molecular formula is C6H5ClN2O2, and it has a molecular weight that reflects its constituent atoms. 6-Chloropicolinic acid is known for its applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as an intermediate in the production of herbicides and other biologically active compounds. Additionally, it may exhibit biological activity, including potential antimicrobial properties. As with many chlorinated compounds, it is important to handle 6-chloropicolinic acid with care, observing appropriate safety protocols due to its potential toxicity and environmental impact.

Formula: C₆H₄ClNO₂

InChI: InChI=1/C6H4ClNO2/c7-5-3-1-2-4(8-5)6(9)10/h1-3H,(H,9,10)

InChI key: InChIKey=ZLKMOIHCHCMSFW-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1N=C(Cl)C=CC1

Synonyms:

• 2-Chloro-6-Pyridine Carboxylic Acid
• 2-Chloropyridine-6-carboxylic acid
• 2-Pyridinecarboxylic acid, 6-chloro-
• 6-Chloro-2-Pyridine Carboxylic Acid
• 6-Chloro-2-pyridinecarboxylic acid
• 6-Chloro-3-picolinic acid
• 6-Chloro-Picolinic Acid
• 6-Chloropyridine-2-Carboxylic Acid
• NSC 51587
• Picolinic acid, 6-chloro-
• 6-Chloropicolinic acid
• 2-Pyridinecarboxylicacid,6-chloro-
• nitrapyrin metabolite
• OTAVA-BB BB5110090024
• 6-CHLOROPYRIDINE-2-CARBOXYLIC ACID 96+%
• 6-chloro-2-pyridinecarboxylicaci
• 6-chloropicolinic
• 6-CHLORO-2-PYRIDINECARBOXYLIC ACID/6-CHLOROPICOLINIC ACID
• 6-CHLORO-2-PICOLINIC ACID
• 6-Chloropyridine-2-carboxylicacid,98%
• 6-CHLORO-2-CARBOXY-PYRIDINE
• 2-CHLORO-6-PYRIDINECARBOXYLIC ACID
• 6-chloro-picolinicaci

6-Chloro-2-pyridinecarboxylic Acid

CAS: 4684-94-0

Formula: C₆H₄ClNO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 157.55

Ref: 3B-C1896

6-Chloropyridine-2-carboxylic acid, 98%

CAS: 4684-94-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₄ClNO₂

Purity: 98%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder

Molecular weight: 157.56

Ref: 02-L19448

2-Pyridinecarboxylic acid, 6-chloro-

CAS: 4684-94-0

Formula: C₆H₄ClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 157.5545

Ref: IN-DA00I8LB

6-Chloro-2-picolinic acid

Controlled Product

CAS: 4684-94-0

Formula: C₆H₄ClNO₂

Color and Shape: Neat

Molecular weight: 157.55

Ref: 04-C11495000

6-Chloropyridine-2-carboxylic acid

CAS: 4684-94-0

6-Chloropyridine-2-carboxylic acid

Formula: C₆H₄ClNO₂

Purity: 98%

Color and Shape: off white solid

Molecular weight: 157.55g/mol

Ref: 54-OR0296

6-Chloropicolinic acid

CAS: 4684-94-0

Formula: C₆H₄ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 157.55

Ref: 10-F013139

6-Chloropyridine-2-carboxylic Acid

Controlled Product

CAS: 4684-94-0

Applications 6-Chloropyridine-2-carboxylic Acid is an intermediate of Sorafenib b(S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
References Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)

Formula: C₆H₄ClNO₂

Color and Shape: Neat

Molecular weight: 157.55

Ref: TR-C380615