CAS 46868-19-3

1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine

Description:

1-Phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine is a bicyclic compound characterized by its unique structure, which includes a benzene ring fused to a nitrogen-containing heterocyclic system. This compound features a tetrahydro configuration, indicating the presence of four hydrogen atoms that saturate the cyclic structure, contributing to its stability and reactivity. The presence of the phenyl group enhances its aromatic characteristics and may influence its solubility and interaction with biological systems. Typically, compounds of this nature may exhibit interesting pharmacological properties, making them of interest in medicinal chemistry. The nitrogen atom in the heterocyclic ring can participate in hydrogen bonding, potentially affecting the compound's biological activity. Additionally, the compound's molecular geometry and electronic properties can influence its reactivity and interactions with other molecules. Overall, 1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine represents a class of compounds that may have applications in drug development and materials science, although specific biological activities would require further investigation.

Formula: C₁₆H₁₇NO

InChI: InChI=1/C16H17NO/c1-2-6-13(7-3-1)16-15-9-5-4-8-14(15)12-17-10-11-18-16/h1-9,16-17H,10-12H2

SMILES: c1ccc(cc1)C1c2ccccc2CNCCO1

Synonyms:

• 1H-2,5-benzoxazocine, 3,4,5,6-tetrahydro-1-phenyl-

N-Desmethylnefopam

CAS: 46868-19-3

N-Desmethylnefopam is the main Nefopam metabolite .

Formula: C₁₆H₁₇NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 239.31

Ref: TM-T19454

N-Desmethyl Nefopam-d5 Hydrochloride (>90%)

Controlled Product

CAS: 46868-19-3

Applications N-Desmethyl Nefopam-D5 is deuterium labelled analogue of N-Desmethyl Nefopam (D422355), which is the main metabolite of Nefopam (N389418), which is a non-opioid non-steroidal centrally acting analgesic.
References Chawla, J., et al.: Ther. Drug Monit., 25, 203 (2003); Aymard, G., et al.: Pharmacol. Toxicol., 92, 279 (2003); Yoon, J., et al.: Korean J. Anesthesiol., 69, 161 (2016); Petrault, M., et al.: Fundam. Clin. Pharmacol., 31, 194 (2017);

Formula: C₁₆H₁₂D₅NO•HCl

Color and Shape: Neat

Molecular weight: 280.8

Ref: TR-D422357

N-Desmethylnefopam

CAS: 46868-19-3

N-Desmethylnefopam is a potent and selective inhibitor of the neuronal nicotinic acetylcholine receptor. The compound binds to the alpha7 subunit of the receptor, but does not bind to other nicotinic acetylcholine receptors. In vitro studies have shown that N-Desmethylnefopam blocks calcium channels and prevents neurotransmitter release. It has also been shown to increase dopamine levels in cells, which may be due to its ability to inhibit reuptake of dopamine by neurons. N-Desmethylnefopam has been shown to be a useful research tool for studying protein interactions, activation, and ligand binding at receptors. This drug has high purity, which makes it suitable for use in life sciences research.

Formula: C₁₆H₁₇NO

Purity: Min. 95%

Molecular weight: 239.31 g/mol

Ref: 3D-WBA86819