AFP-464, with the CAS number 468719-52-0, is a synthetic compound that belongs to the class of small molecules known for their potential therapeutic applications, particularly in oncology. It is characterized by its unique chemical structure, which includes specific functional groups that contribute to its biological activity. AFP-464 has been studied for its ability to inhibit certain cellular pathways involved in cancer cell proliferation and survival. Its mechanism of action typically involves interference with DNA synthesis or repair processes, making it a candidate for targeted cancer therapies. The compound is often evaluated in preclinical and clinical settings to assess its efficacy, safety, and pharmacokinetic properties. As with many investigational drugs, the characteristics of AFP-464, including its solubility, stability, and interaction with biological systems, are critical for understanding its potential as a therapeutic agent. Further research is necessary to fully elucidate its properties and therapeutic potential in various cancer types.

AFP-464

468719-52-0: AFP-464, with the CAS number 468719-52-0, is a synthetic compound that belongs to the class of small molecules known for their potential therapeutic applications, particularly in oncology. It is characterized by its unique chemical structure, which includes specific functional groups that contribute to its biological activity. AFP-464 has been studied for its ability to inhibit certain cellular pathways involved in cancer cell proliferation and survival. Its mechanism of action typically involves interference with DNA synthesis or repair processes, making it a candidate for targeted cancer therapies. The compound is often evaluated in preclinical and clinical settings to assess its efficacy, safety, and pharmacokinetic properties. As with many investigational drugs, the characteristics of AFP-464, including its solubility, stability, and interaction with biological systems, are critical for understanding its potential as a therapeutic agent. Further research is necessary to fully elucidate its properties and therapeutic potential in various cancer types.

<p>AFP 464 is an activating agent that binds to the molecular target, which is thought to be growth rate. AFP 464 has been shown to increase the activation of cancer cells and cause a change in their phenotype. It also has anti-tumor effects on kidney cancer cells and other carcinoma cells. AFP 464 is potently activated by spontaneous sequestration or postulated mechanisms. Treatment with AFP 464 has been shown to produce a decrease in tumor size and weight as well as an increase in life span for mice with kidney cancer.</p>

AFP 464

AFP464 (NSC710464) free base is an active HIF-1α inhibitor (IC50: 0.25 μM) and a potent aryl hydrocarbon receptor (AhR) activator.

CAS 468719-52-0

AFP-464

AFP 464

Ref: 3D-TTA71952

AFP464 free base

Ref: TM-T10258