CAS 469-21-6: (±)-Doxylamine

Description: (±)-Doxylamine is an antihistamine belonging to the ethanolamine class, primarily used for its sedative and anti-allergic properties. It is a racemic mixture, meaning it contains equal parts of two enantiomers, which can exhibit different biological activities. The substance is typically encountered as a white to off-white crystalline powder, and it is soluble in water and alcohol, making it suitable for various formulations. Doxylamine acts by blocking the H1 histamine receptors, thereby alleviating symptoms of allergies and providing relief from insomnia due to its sedative effects. It is commonly found in over-the-counter sleep aids and cold medications. The compound has a relatively low toxicity profile when used as directed, but it can cause side effects such as drowsiness, dry mouth, and dizziness. Due to its sedative properties, caution is advised when operating machinery or driving after consumption. Overall, (±)-Doxylamine is a versatile compound with applications in both allergy relief and sleep management.

Formula: C₁₇H₂₂N₂O

InChI: InChI=1S/C17H22N2O/c1-17(20-14-13-19(2)3,15-9-5-4-6-10-15)16-11-7-8-12-18-16/h4-12H,13-14H2,1-3H3

InChI key: InChIKey=HCFDWZZGGLSKEP-UHFFFAOYSA-N

SMILES: N=1C=CC=CC1C(OCCN(C)C)(C=2C=CC=CC2)C

Synonyms:

• (.+-.)-Doxylamine
• 2-[α-[2-(Dimethylamino)ethoxy]-α-methylbenzyl]pyridine
• Donormil
• Doxilminio
• Doxylamin
• Ls 127
• N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine
• Pyridine, 2-[α-[2-(dimethylamino)ethoxy]-α-methylbenzyl]-
• Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-
• dimethyl(2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl)amine

Doxylamine Succinate

CAS: 469-21-6562-10-7

• Formula: C₁₇H₂₂N₂O·C₄H₆O₄
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 388.46

Doxylamine

CAS: 469-21-6

• Formula: C₁₇H₂₂N₂O
• Molecular weight: 270.38

S-Doxylamine

CAS: 469-21-6

Applications S-Doxylamine is a first-​generation antihistamine and a sedative. Doxylamine is used to treat nausea …

• Formula: C₁₇H₂₂N₂O
• Color and Shape: Neat
• Molecular weight: 270.37

(±)-Doxylamine

CAS: 469-21-6

Stability Temperature Sensitive Applications (±)-Doxylamine is an intermediate in the synthesis of Doxylamine N, N’-Dioxide …

• Formula: C₁₇H₂₂N₂O
• Color and Shape: Neat
• Molecular weight: 270.37

Dimethyl({2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethyl})amine

CAS: 469-21-6

Please enquire for more information about Dimethyl({2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethyl})amine including the price, delivery time and more detailed …

• Formula: C₁₇H₂₂N₂O
• Purity: Min. 95%
• Molecular weight: 270.37 g/mol