CAS 469-59-0: Jervine
Description:Jervine is a naturally occurring alkaloid primarily found in certain plant species, particularly in the family of plants known as the Liliaceae. It is classified as a steroidal alkaloid and is structurally related to other compounds such as veratramine and cyclopamine. Jervine is characterized by its complex steroid structure, which contributes to its biological activity. It exhibits a range of pharmacological effects, including potential neurotoxic properties, and has been studied for its impact on various physiological processes. The compound is known to interact with specific receptors in the nervous system, which can lead to both therapeutic and toxicological implications. Due to its biological activity, jervine has garnered interest in medicinal chemistry and pharmacology, although its use is limited due to safety concerns. As with many alkaloids, handling jervine requires caution due to its potential toxicity and the need for further research to fully understand its effects and applications.
Formula:C27H39NO3
InChI:InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1
InChI key:InChIKey=CLEXYFLHGFJONT-DNMILWOZSA-N
SMILES:O=C1C2=C(C)C3(OC4CC(C)CNC4C3C)CCC2C5CC=C6CC(O)CCC6(C)C15
- Synonyms:
- (2′R,3S,3′R,3′aS,6′S,6aS,6bS,7′aR,11aS,11bR)-2,3,3′a,4,4′,5′,6,6′,6a,6b,7,7′,7′a,8,11a,11b-Hexadecahydro-3-hydroxy-3′,6′,10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2′(3′H)-furo[3,2-b]pyridin]-11(1H)-one
- (3beta,22S,23R)-3-hydroxy-17,23-epoxyveratraman-11-one
- 17,23beta-Epoxy-3beta-hydroxyveratraman-11-one
- Brn 0059109
- Hsdb 3502
- Iervin
- Jervin
- Jerwiny
- Nsc 23898
- Nsc 7520
- See more synonyms
- Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)-pyridin)-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy- 3',6',10,11b-tetramethyl-
- Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)-pyridin)-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10, 11B-tetramethyl-
- Spiro[9H-benzo[a]fluorene-9,2′(3′H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3′a,4,4′,5′,6,6′,6a,6b,7,7′,7′a,8,11a,11b-hexadecahydro-3-hydroxy-3′,6′,10,11b-tetramethyl-, (2′R,3S,3′R,3′aS,6′S,6aS,6bS,7′aR,11aS,11bR)-
- Spiro[9H-benzo[a]fluorene-9,2′(3′H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3′a,4,4′,5′,6,6′,6a,6b,7,7′,7′a,8,11a,11b-hexadecahydro-3-hydroxy-3′,6′,10,11b-tetramethyl-, [3S-(3α,6aα,6bβ,9α(3′S*,3′aR*,6′R*,7′aS*),11aβ,11bα)]-
- Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3-beta,23-beta)-
- Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3beta,23beta)-
- Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3β,23β)-
- Jervine
