CAS 4707-49-7

2,4-Dihydroxy-3-methylbenzoic acid

Description:

2,4-Dihydroxy-3-methylbenzoic acid, also known as salicylic acid methyl derivative, is an organic compound characterized by its aromatic structure featuring a benzoic acid core with two hydroxyl groups and a methyl group. This compound is typically a white to off-white crystalline solid, soluble in alcohol and slightly soluble in water, reflecting its polar functional groups. It exhibits acidic properties due to the carboxylic acid group, allowing it to participate in various chemical reactions, including esterification and amidation. The presence of hydroxyl groups contributes to its potential as a phenolic antioxidant and its ability to form hydrogen bonds, influencing its reactivity and interactions with other molecules. Additionally, 2,4-Dihydroxy-3-methylbenzoic acid may have applications in pharmaceuticals and as an intermediate in organic synthesis. Its CAS number, 4707-49-7, is a unique identifier that facilitates its recognition in chemical databases and regulatory frameworks. Overall, this compound's structural features and functional groups make it a subject of interest in both research and industrial applications.

Formula: C₈H₈O₄

InChI: InChI=1S/C8H8O4/c1-4-6(9)3-2-5(7(4)10)8(11)12/h2-3,9-10H,1H3,(H,11,12)

InChI key: InChIKey=KZCSDJKWEYGAIX-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(O)C(C)=C(O)C=C1

Synonyms:

• 2,4-Dihydroxy-m-toluate
• 3-Methyl-2,4-dihydroxybenzoic acid
• Benzoic Acid, 2,4-Dihydroxy-3-Methyl-
• β-Resorcylic acid, 3-methyl-
• 2,4-Dihydroxy-3-methylbenzoic acid

2,4-Dihydroxy-3-methylbenzoic acid

CAS: 4707-49-7

2,4-Dihydroxy-3-methylbenzoic acid (2,4-DMB) is a potent compound that has been shown to have chemotherapeutic properties. It is a DNA repair agent that also inhibits the activity of topoisomerase II and DNA polymerase III. 2,4-DMB can be used in the treatment of radiation and ionizing radiation induced cancers. The pharmacophore of 2,4-DMB has been identified as being composed of three hydrophobic regions and one hydrophilic region. This pharmacophore has been used to design other potent compounds with similar activity against cancer cells.

Formula: C₈H₈O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 168.15 g/mol

Ref: 3D-FD66514

2,4-Dihydroxy-3-methylbenzoic Acid

Controlled Product

CAS: 4707-49-7

Applications 2,4-Dihydroxy-3-methylbenzoic acid is used in the synthesis of Averufin a useful intermediate in Aflatoxin B1 biosynthesis.
References Townsend, C. A., et al.: J. Chem. Soc. Perkin 1, 1972, 839 (1988)

Formula: C₈H₈O₄

Color and Shape: Neat

Molecular weight: 168.147

Ref: TR-D494963