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CAS 47082-97-3

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Pargolol

Description:
Pargolol, with the CAS number 47082-97-3, is a chemical compound classified as a beta-adrenergic antagonist, commonly known as a beta-blocker. It is primarily used in the treatment of cardiovascular conditions, such as hypertension and certain types of arrhythmias. Pargolol works by blocking the action of epinephrine and norepinephrine on beta-adrenergic receptors, leading to a decrease in heart rate and blood pressure. The compound is characterized by its ability to reduce cardiac output and myocardial oxygen demand, making it beneficial for patients with heart-related issues. Additionally, Pargolol may exhibit varying degrees of selectivity for beta-1 and beta-2 receptors, influencing its therapeutic profile and side effects. As with other beta-blockers, potential side effects can include fatigue, dizziness, and respiratory issues, particularly in individuals with pre-existing conditions. Overall, Pargolol represents a significant option in the pharmacological management of cardiovascular diseases, contributing to improved patient outcomes when used appropriately.
Formula:C16H23NO3
InChI:InChI=1S/C16H23NO3/c1-5-10-19-14-8-6-7-9-15(14)20-12-13(18)11-17-16(2,3)4/h1,6-9,13,17-18H,10-12H2,2-4H3
InChI key:InChIKey=UFNAECVCKNHAKN-UHFFFAOYSA-N
SMILES:O(CC(CNC(C)(C)C)O)C1=C(OCC#C)C=CC=C1
Synonyms:
  • 1-(tert-Butylamino)-3-(2-(prop-2-ynyloxy)phenoxy)propan-2-ol
  • Pargolol
  • 1-[(1,1-Dimethylethyl)amino]-3-[2-(2-propyn-1-yloxy)phenoxy]-2-propanol
  • 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[2-(2-propynyloxy)phenoxy]-
  • 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[2-(2-propyn-1-yloxy)phenoxy]-
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