CAS 471-15-8: (+)-Thujone

Description:(+)-Thujone is a monoterpene ketone primarily found in various plants, notably in wormwood (Artemisia absinthium) and sage (Salvia spp.). It is characterized by its distinct minty, camphoraceous aroma and is often associated with the flavor profile of absinthe. The compound has a molecular formula of C10H16O and features a bicyclic structure, which contributes to its unique properties. (+)-Thujone exists in two stereoisomeric forms, with the (+) configuration being the more prevalent in nature. It exhibits moderate volatility and is soluble in organic solvents but has limited solubility in water. In terms of biological activity, thujone has been studied for its potential neurotoxic effects, particularly at high concentrations, and is known to interact with the GABA receptor system, which may lead to excitatory effects in the central nervous system. Due to its psychoactive properties, the use of thujone in food and beverages is regulated in many countries. Overall, (+)-Thujone is a compound of interest in both culinary and pharmacological contexts.

Formula:C₁₀H₁₆O

InChI:InChI=1/C10H16O/c1-6(2)10-4-8(10)7(3)9(11)5-10/h6-8H,4-5H2,1-3H3/t7-,8+,10-/m0/s1

InChI key:InChIKey=USMNOWBWPHYOEA-XKSSXDPKSA-N

SMILES:O=C1CC2(CC2C1C)C(C)C

Synonyms:
(+)-Isothujone
(+)-Thujone
(+)-b-Thujone
(1S,4S,5R)-1-Isopropyl-4-methylbicyclo[3.1.0]hexan-3-one
(1S,4S,5R)-4-methyl-1-(1-methylethyl)bicyclo[3.1.0]hexan-3-one
.beta.-Thujone
3-Thujanone, (1S,4S,5R)-(+)-
4-Methyl-1-(1-methylethyl)-[1S-(1α,4β,5α)]-bicyclo[3.1.0]hexan-3-one
471-15-8
Bicyclo[3.1.0]hexan-3-one, 4-methyl-1-(1-methylethyl)-, [1S-(1α,4β,5α)]-
See more synonyms
NSC 67392
[1S-(1a,4b,5a)]-4-Methyl-1-(1-methylethyl)bicyclo[3.1.0]hexan-3-one
bicyclo[3.1.0]hexan-3-one, 4-methyl-1-(1-methylethyl)-, (1S,4S,5R)-
cis-Thujone
d-Isothujone
d-β-Thujone
beta-Thujon
ALPHA,BETA-THUJONE
(+)-3-Thujone
(E)-Thujone
trans-Thujone
THUJONE ALPHA AND BETA
(-)-1-ISOPROPYL-4-METHYLBICYCLO[3.1.0]HEXAN-3-ONE
Thujone trans
(+)-Isothujon
Bicyclo[3.1.0]hexan-3-one, 4-methyl-1-(1-methylethyl)-, [1S-(1alpha,4beta,5alpha)]-
1-ISOPROPYL-4-METHYLBICYCLO[3.1.0]HEXAN-3-ONE (CIS AND TRANS)
Thujone cis
THUJONE-A AND B
ALPHA AND BETA-THUJONE
D-beta-Thujone
(Z)-thujone