CAS 471-54-5

(1R,4S,4aS,6aR,9R,10aR,10bR)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c′]dipyran-3,7-dione

Description:

The chemical substance with the name "(1R,4S,4aS,6aR,9R,10aR,10bR)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c′]dipyran-3,7-dione" and CAS number 471-54-5 is a complex organic compound characterized by its multi-ring structure and specific stereochemistry. It features a fused bicyclic system that includes a benzo-dipyran moiety, which contributes to its potential biological activity. The presence of a furan ring indicates possible reactivity and interactions with biological systems. This compound is likely to exhibit properties such as solubility in organic solvents, and it may have applications in pharmaceuticals or natural product chemistry due to its structural complexity. The hydroxyl group suggests it may participate in hydrogen bonding, influencing its solubility and reactivity. Overall, this substance exemplifies the intricate nature of organic compounds, particularly those derived from natural sources or designed for specific functions in medicinal chemistry.

Formula: C₂₀H₂₂O₆

InChI: InChI=1S/C20H22O6/c1-18-9-14(11-5-8-24-10-11)25-16(21)12(18)3-6-19(2)15(18)13-4-7-20(19,23)17(22)26-13/h4-5,7-8,10,12-15,23H,3,6,9H2,1-2H3/t12-,13-,14+,15+,18-,19-,20+/m0/s1

InChI key: InChIKey=AALLCALQGXXWNA-VBFYFJBNSA-N

SMILES: C[C@@]12[C@@]([C@]3(C)[C@@](CC1)(C(=O)O[C@H](C3)C=4C=COC4)[H])([C@]5(OC(=O)[C@]2(O)C=C5)[H])[H]

Synonyms:

• Isocolumbin
• 1,4-Etheno-3H,7H-benzo[1,2-c:3,4-c′]dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, (1R,4S,4aS,6aR,9R,10aR,10bR)-
• 1,4-Etheno-3H,7H-benzo[1,2-c:3,4-c′]dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, [1R-(1α,4β,4aα,6aα,9β,10aβ,10bα)]-
• (1R,4S,4aS,6aR,9R,10aR,10bR)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c′]dipyran-3,7-dione
• (1R,4S,6aβ,10bβ)-Decahydro-9α-(3-furyl)-4-hydroxy-4aβ,10aα-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione

Isocolumbin

CAS: 471-54-5

Formula: C₂₀H₂₂O₆

Molecular weight: 358.39

Ref: 7W-GY7716

Isocolumbin

CAS: 471-54-5

Isocolumbin has anti-inflammatory, and antimicrobial activities.

Formula: C₂₀H₂₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 358.39

Ref: TM-TN1133

Isocolumbin

CAS: 471-54-5

Formula: C₂₀H₂₂O₆

Purity: 95%~99%

Molecular weight: 358.39

Ref: BP-BP0777

Isocolumbin

CAS: 471-54-5

Isocolumbin is a natural compound that has been shown to have significant cytotoxicity against the human breast cancer cell line MDA-MB-231. The active form of Isocolumbin is columbin, which can be isolated from the plant Stephania dahurica. It was found to have hypoglycemic effects in an untreated group of rats and also showed significant cytotoxicity against chronic cough cells. Isocolumbin has been shown to bind with high affinity to dopamine D2 receptors and serotonin 5-HT2A receptors, which are involved in the regulation of numerous physiological functions including mood, appetite, sleep, cognition, and pain sensation.

Formula: C₂₀H₂₂O₆

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 358.39 g/mol

Ref: 3D-FI65689