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CAS 473-27-8

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4-(Trifluoromethylsulfonyl)aniline

Description:
4-(Trifluoromethylsulfonyl)aniline, with the CAS number 473-27-8, is an organic compound characterized by the presence of both an aniline group and a trifluoromethylsulfonyl functional group. This compound typically appears as a solid and is known for its high reactivity due to the strong electron-withdrawing nature of the trifluoromethylsulfonyl group, which can significantly influence its chemical behavior. It is often utilized in various chemical synthesis processes, particularly in the development of pharmaceuticals and agrochemicals, due to its ability to act as a sulfonylating agent. The presence of the trifluoromethyl group enhances its lipophilicity and stability, making it a valuable intermediate in organic synthesis. Additionally, this compound may exhibit unique physical properties, such as solubility in polar organic solvents, and can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.
Formula:C7H6F3NO2S
InChI:InChI=1/C7H6F3NO2S/c8-7(9,10)14(12,13)6-3-1-5(11)2-4-6/h1-4H,11H2
SMILES:c1cc(ccc1N)S(=O)(=O)C(F)(F)F
Synonyms:
  • 4-[(Trifluoromethyl)sulfonyl]aniline
  • 4-[(Trifluoromethyl)sulfonyl]phenylamine
  • 4-Aminophenyl trifluoromethyl sulfone
  • 4-Aminophenyl trifluoromethyl sulphone
  • Benzenamine, 4-[(Trifluoromethyl)Sulfonyl]-
  • p-(Trifluoromethylsulfonyl)aniline
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