CAS 473-98-3

Betulin

Description:

Betulin is a naturally occurring triterpenoid compound primarily extracted from the bark of birch trees, particularly Betula species. It is characterized by its white crystalline appearance and has a molecular formula of C30H50O2. Betulin exhibits a range of biological activities, including anti-inflammatory, antioxidant, and anticancer properties, making it of interest in pharmaceutical and nutraceutical applications. Its structure features a pentacyclic triterpene framework, which contributes to its diverse biological effects. Betulin is also known for its potential in promoting skin health and has been studied for its ability to enhance wound healing. Additionally, it can be converted into other derivatives, such as betulinic acid, which further expands its potential therapeutic uses. Due to its natural origin and beneficial properties, betulin is gaining attention in the fields of medicine and cosmetics. However, further research is needed to fully understand its mechanisms of action and potential applications in various health-related fields.

Formula: C₃₀H₅₀O₂

InChI: InChI=1S/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22-,23+,24-,25+,27-,28+,29+,30+/m0/s1

InChI key: InChIKey=FVWJYYTZTCVBKE-ROUWMTJPSA-N

SMILES: C(O)[C@]12[C@@]([C@@]3([C@](C)([C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)[C@@H](O)CC5)[H])[H])CC1)[H])([C@H](C(C)=C)CC2)[H]

Synonyms:

• (3Beta)-Lup-20(29)-Ene-3,28-Diol
• (3Beta,5Xi,9Xi,13Xi,14Xi,18Xi,19Xi)-Lup-20(29)-Ene-3,28-Diol
• (3Beta,5Xi,9Xi,18Xi)-Lup-20(29)-Ene-3,28-Diol
• (3β)-Lup-20(29)-ene-3,28-diol
• 3,28-Dihydroxy-lupeol
• 3aH-Cyclopenta[a]chrysene, lup-20(29)-ene-3,28-diol deriv.
• 3β,28-Dihydroxylup-20(29)-ene
• Betuline
• Betulinic alcohol
• Betulinol
• Betulol
• Lup-20(29)-Ene-3,28-Diol
• Lup-20(29)-en-3,28-diol, (3β)-
• Lup-20(29)-ene-3,28-diol, (3β)-
• Lup-20(29)-ene-3β,28-diol
• Lup-20(30)-ene-3β,28-diol
• Lupene-20(29) Diol-3,28, (3Β)-
• Nsc 4644

Betulinol

CAS: 473-98-3

Formula: C₃₀H₅₀O₂

Purity: >97.0%(GC)

Color and Shape: White to Light yellow powder to crystaline

Molecular weight: 442.73

Ref: 3B-B0803

Betulin

CAS: 473-98-3

Betulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₀H₅₀O₂

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 442.73

Ref: 11-0018S

Lup-20(29)-ene-3b,28-diol

CAS: 473-98-3

Formula: C₃₀H₅₀O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 442.7168

Ref: IN-DA0039BK

Betulin

CAS: 473-98-3

Betulin

Purity: ≥98%

Molecular weight: 442.72g/mol

Ref: 54-BUP15988

Betulin

CAS: 473-98-3

Formula: C₃₀H₅₀O₂

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 442.72

Ref: 7W-GP5633

Betulin

CAS: 473-98-3

Formula: C₃₀H₅₀O₂

Purity: 95%~99%

Molecular weight: 442.728

Ref: BP-BP0269

Betulin

CAS: 473-98-3

Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene.

Formula: C₃₀H₅₀O₂

Purity: 98.52% - 99.88%

Color and Shape: White Crystalline Powder

Molecular weight: 442.72

Ref: TM-T3121

Betulin

CAS: 473-98-3

Cyclic alcohol

Formula: C₃₀H₅₀O₂

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 442.73

Ref: 5G-89581

Betulin

Controlled Product

CAS: 473-98-3

Stability Hygroscopic
Applications Betulin is a derivative of Betulinic Acid (B330250), used in the treatment of cancer and HIV disease. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity
References Cichewicz, R. et al.: Med. Res. Rev., 24, 90 (2003); Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010);

Formula: C₃₀H₅₀O₂

Color and Shape: White Powder

Molecular weight: 442.72

Ref: TR-B330240

Betulin

Controlled Product

CAS: 473-98-3

Betulin is a natural compound found in the bark of the birch tree. It has potent angiogenic properties and induces the growth of new blood vessels. Betulin also has anti-inflammatory activity and has been shown to inhibit the production of pro-inflammatory cytokines, such as TNF-α, IL-1β, and IL-6. Betulin is a potent inducer of apoptosis in human cancer cells. It also inhibits the mitochondrial membrane potential, which results in cell death. This drug also appears to have an effect on oral pathogens by reducing their virulence and ability to adhere to epithelial cells. In addition, betulin can be used as an analytical reference standard for preparative high performance liquid chromatography (HPLC). Experimental studies have shown that betulin interacts with drugs that are metabolized by cytochrome P450 enzymes.

Formula: C₃₀H₅₀O₂

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 442.72 g/mol

Ref: 3D-FB29605

Betulin

CAS: 473-98-3

Formula: C₃₀H₅₀O₂

Purity: 95.0%

Molecular weight: 442.728

Ref: 10-F547257

Betulin-d3

Controlled Product

CAS: 473-98-3

Applications Betulin-d3 is the isotope labelled analog of Betulin (B330240); a derivative of Betulinic Acid (B330250) which is a compound used in the treatment of cancer and HIV disease. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity
References Cichewicz, R. et al.: Med. Res. Rev., 24, 90 (2003); Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010)

Formula: C₃₀H₄₇D₃O₂

Color and Shape: Neat

Molecular weight: 445.74

Ref: TR-B330242

Betulin

CAS: 473-98-3

Betulin

Purity: 98%

Molecular weight: 442.72g/mol

Ref: 54-BIK9003