CAS 473278-54-5

2-amino-9-[(2R,3S,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl]-1H-purin-6-one

Description:

2-amino-9-[(2R,3S,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl]-1H-purin-6-one, with CAS number 473278-54-5, is a purine derivative characterized by its complex structure that includes both amino and hydroxyl functional groups. This compound features a purine base, which is a key component of nucleic acids, and a sugar moiety derived from tetrahydrofuran, indicating its potential role in biological systems, particularly in nucleoside analogs. The presence of a methoxyethoxy group suggests enhanced solubility and stability, which may influence its pharmacological properties. The stereochemistry indicated by the (2R,3S,4S,5R) configuration is crucial for its biological activity, as it can affect interactions with enzymes and receptors. Overall, this compound may exhibit interesting biochemical properties, making it a candidate for further research in medicinal chemistry and drug development, particularly in the context of antiviral or anticancer therapies.

Formula: C₁₃H₁₉N₅O₆

InChI: InChI=1/C13H19N5O6/c1-22-2-3-23-9-8(20)6(4-19)24-12(9)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-6,8-9,12,19-20H,2-4H2,1H3,(H3,14,16,17,21)/t6-,8+,9+,12-/m1/s1

Synonyms:

• 2'-O-(2-methoxyethyl)-guanosine

2'-O-(2-Methoxyethyl)guanosine

CAS: 473278-54-5

Formula: C₁₃H₁₉N₅O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 341.3199

Ref: IN-DA00DFG0

2-Amino-9-((2R,3R,4R,5R)-4-Hydroxy-5-(Hydroxymethyl)-3-(2-Methoxyethoxy)Tetrahydrofuran-2-Yl)-3H-Purin-6(9H)-One

CAS: 473278-54-5

2-Amino-9-((2R,3R,4R,5R)-4-Hydroxy-5-(Hydroxymethyl)-3-(2-Methoxyethoxy)Tetrahydrofuran-2-Yl)-3H-Purin-6(9H)-One

Purity: 97%

Molecular weight: 341.32g/mol

Ref: 54-OR1028841

2'-O-(2-Methoxyethyl)guanosine

CAS: 473278-54-5

2'-O-(2-Methoxyethyl)guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. This compound has been shown to react with aromatic hydrocarbons to form a reagent that is useful for the alkylation of nucleophilic groups in organic synthesis.

Formula: C₁₃H₁₉N₅O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 341.32 g/mol

Ref: 3D-NM57537

2′-O-(2-Methoxyethyl)guanosine

CAS: 473278-54-5

Purity: 98%

Molecular weight: 341.324

Ref: 10-F987051

2'-O-(2-Methoxyethyl)guanosine

Controlled Product

CAS: 473278-54-5

Formula: C₁₃H₁₉N₅O₆

Color and Shape: Neat

Molecular weight: 341.32

Ref: TR-M262525

2′-O-(2-Methoxyethyl)guanosine

CAS: 473278-54-5

2'-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a modified nucleoside, can be enzymatically converted from 2'-O-(2-methoxyethyl)-2,6-diaminopurine riboside by adenosine deaminase; however, it is not readily phosphorylated by cytosolic nucleoside kinases and cannot be incorporated into cellular DNA or RNA.

Formula: C₁₃H₁₉N₅O₆

Color and Shape: Solid

Molecular weight: 341.32

Ref: TM-T40566