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CAS 473416-81-8

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4-fluoro-1H-indazole-5-carbonitrile

Description:
4-Fluoro-1H-indazole-5-carbonitrile is a chemical compound characterized by its indazole core, which is a bicyclic structure containing a five-membered ring fused to a six-membered ring. The presence of a fluorine atom at the 4-position and a cyano group (-C≡N) at the 5-position contributes to its unique chemical properties. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. It is of interest in medicinal chemistry and drug development due to its potential biological activity, particularly in the context of targeting specific receptors or enzymes. The cyano group can participate in various chemical reactions, making it a versatile building block for further synthetic modifications. Additionally, the fluorine atom can influence the compound's lipophilicity and metabolic stability, which are critical factors in pharmacokinetics. As with many chemical substances, safety precautions should be observed when handling 4-fluoro-1H-indazole-5-carbonitrile, as it may pose health risks if ingested or inhaled.
Formula:C8H4FN3
InChI:InChI=1/C8H4FN3/c9-8-5(3-10)1-2-7-6(8)4-11-12-7/h1-2,4H,(H,11,12)
SMILES:c1cc2c(c[nH]n2)c(c1C#N)F
Synonyms:
  • 1H-Indazole-5-carbonitrile, 4-fluoro-
  • 5-Cyano-4-fluoro (1H)indazole
  • 4-Fluoro-1H-indazole-5-carbonitrile
  • 1H-Indazole-5-carbonitrile,4-fluoro-(9CI)
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