CAS 474-74-8
:Glycolithocholic acid
Description:
Glycolithocholic acid, with the CAS number 474-74-8, is a bile acid derivative that plays a significant role in the digestion and absorption of fats in the intestine. It is a conjugated bile acid formed from lithocholic acid and glycine, which enhances its solubility and biological activity. Glycolithocholic acid is characterized by its amphipathic nature, possessing both hydrophilic and hydrophobic properties, allowing it to interact effectively with lipids and facilitate their emulsification. This compound is typically found in the bile of various mammals and is involved in the enterohepatic circulation. Its structure includes a steroid nucleus with hydroxyl groups that contribute to its solubility in aqueous environments. Glycolithocholic acid has been studied for its potential implications in various physiological processes, including cholesterol metabolism and the regulation of lipid homeostasis. Additionally, it may have implications in certain pathological conditions, making it a subject of interest in biomedical research.
Formula:C26H43NO4
InChI:InChI=1S/C26H43NO4/c1-16(4-9-23(29)27-15-24(30)31)20-7-8-21-19-6-5-17-14-18(28)10-12-25(17,2)22(19)11-13-26(20,21)3/h16-22,28H,4-15H2,1-3H3,(H,27,29)(H,30,31)/t16-,17-,18-,19+,20-,21+,22+,25+,26-/m1/s1
InChI key:InChIKey=XBSQTYHEGZTYJE-OETIFKLTSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H]
Synonyms:- 3α-Hydroxy-5β-cholanic acid glycine ester
- 3α-Hydroxy-5β-cholanoylglycine
- 3α-Hydroxy-N-(carboxymethyl)-5β-cholan-24-amide
- 5β-Cholan-24-amide, N-(carboxymethyl)-3α-hydroxy-
- 79252-50-9
- Cholane, glycine deriv.
- Glycine, N-(3α-hydroxy-5β-cholan-24-oyl)-
- Glycine, N-[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]-
- Glycolithocholic acid
- Lithocholic acid glycine conjugate
- Lithocholylglycine
- N-(3α-Hydroxy-5β-cholanoyl)glycine
- See more synonyms
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Found 8 products.
Glycine, N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-
CAS:Formula:C26H43NO4Purity:98%Color and Shape:SolidMolecular weight:433.6239Lithocholylglycine-d5 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase.<br>References Ishikawa, H., et al.: J. Lipid. Res., 40, 1920 (1999), Gustafsson, U., et al.: Eur. J. Clin. Invest., 30, 1099 (2000), Gowda, G., et al.: Lipids, 41, 591 (2006), Lindon, J., et al.: Pharm. Res., 23, 1075 (2006),<br></p>Formula:C26H38D5NO4Color and Shape:NeatMolecular weight:438.65Lithocholylglycine
CAS:Controlled Product<p>Applications A metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase.<br>References Ishikawa, H., et al.: J. Lipid. Res., 40, 1920 (1999), Gustafsson, U., et al.: Eur. J. Clin. Invest., 30, 1099 (2000), Gowda, G., et al.: Lipids, 41, 591 (2006), Lindon, J., et al.: Pharm. Res., 23, 1075 (2006),<br></p>Formula:C26H43NO4Color and Shape:Off-WhiteMolecular weight:433.62Lithocholylglycine
CAS:<p>Lithocholylglycine is a bile acid that is conjugated with glycine, which is the first step in the synthesis of bile acids. Lithocholylglycine has been found to be useful as an analytical tool for determining serum bile acids and can be used as a biological marker for liver function. This compound also has anticancer and anti-inflammatory properties and may be useful in clinical pathology, especially in cases of hepatitis or diabetes. Lithocholylglycine has been shown to have cholinergic activity and to decrease blood glucose levels in diabetic patients.</p>Formula:C26H43NO4Purity:(%) Min. 98%Color and Shape:White PowderMolecular weight:433.62 g/molGlycolithocholic acid
CAS:Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.Formula:C26H43NO4Purity:99.75% - 99.83%Color and Shape:SolidMolecular weight:433.62
![Glycine, N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0070G1.jpg&w=3840&q=75)
