CAS 474-86-2

Equilin

Description:

Equilin is a naturally occurring estrogenic steroid, primarily derived from the urine of pregnant mares, and is classified as a conjugated estrogen. Its chemical structure is characterized by a phenolic A-ring and a ketone group at the C-17 position, which contributes to its biological activity. Equilin is often used in hormone replacement therapy and is known for its ability to bind to estrogen receptors, thereby exerting estrogenic effects in the body. It has been studied for its potential benefits in alleviating menopausal symptoms and its role in bone health. However, like other estrogens, it may also be associated with certain risks, including an increased likelihood of thromboembolic events and potential impacts on breast and endometrial tissue. The substance is typically administered in various formulations, including tablets and injections, and is subject to regulatory oversight due to its hormonal activity. As with any hormone therapy, careful consideration of benefits versus risks is essential in clinical practice.

Formula: C₁₈H₂₀O₂

InChI: InChI=1S/C18H20O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3-5,10,14,16,19H,2,6-9H2,1H3/t14-,16+,18+/m1/s1

InChI key: InChIKey=WKRLQDKEXYKHJB-HFTRVMKXSA-N

SMILES: C[C@@]12[C@](C=3[C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])(CCC2=O)[H]

Synonyms:

• (9Xi,14Xi)-3-Hydroxyestra-1,3,5(10),7-Tetraen-17-One
• 1,3,5,7-Estratetraen-3-ol-17-one
• 3-Hydroxyestra-1,3,5(10),7-Tetraen-17-One
• 3-Hydroxyoestra-1,3,5(10),7-Tetraen-17-One
• 7-Dehydroestrone
• Estra-1,3,5(10),7-tetraen-17-one, 3-hydroxy-
• NSC 10971
• Equilin

EQUILIN CRS

CAS: 474-86-2

EQUILIN CRS

Formula: C₁₈H₂₀O₂

Color and Shape: Added

Molecular weight: 268.3502

Ref: 41-Y0000052

Equilin

CAS: 474-86-2

Estrogens and progestins

Formula: C₁₈H₂₀O₂

Color and Shape: White Off-White Powder

Molecular weight: 268.14633

Ref: 45-1238002

Equilin

CAS: 474-86-2

Formula: C₁₈H₂₀O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 268.3502

Ref: IN-DA00JO2E

Equilin

CAS: 474-86-2

Equilin

Purity: ≥98%

Molecular weight: 268.35g/mol

Ref: 54-BUP21385

Equilin

CAS: 474-86-2

Formula: C₁₈H₂₀O₂

Color and Shape: White To Off-White Solid

Molecular weight: 268.36

Ref: 4Z-E-306

Equilin

Controlled Product

CAS: 474-86-2

Formula: C₁₈H₂₀O₂

Color and Shape: Neat

Molecular weight: 268.35

Ref: 04-C13193050

Equilin

Controlled Product

CAS: 474-86-2

Formula: C₁₈H₂₀O₂

Color and Shape: Neat

Molecular weight: 268.35

Ref: 86-MM1240.00

Equilin

CAS: 474-86-2

Equilin (7-Dehydroestrone) is a neurotrophic estrogenic steroid with vasodilatory activity used in the study of hypertension.

Formula: C₁₈H₂₀O₂

Purity: 98.57% - 99.72%

Molecular weight: 268.35

Ref: TM-T13684

Equilin

CAS: 474-86-2

Applications Equilin is an estrogen found in Premarin, which is a mixture of conjugated estrogens widely used in hormone replacement therapy and effecting cellular network structure (1). It may induce mammary tumors in rats (2). Implicated in drugs that shift energy metabolism from mitochondrial respiration to glycolysis (3). Estrogen derivative (4).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Fliri, A. et al.: J. Med. Chem. 2009 Dec 24;52(24):8038-46.2. Okamoto Y. et al.: Toxicol. Lett. 2010 Apr 1;193(3):224-8.3. Gohil, V. et al.: Nat. Biotechnol. 2010 Mar;28(3):249-554. Suri, R. et al.: Environ. Sci. Technol. 2010 Feb 15;44(4):1

Formula: C₁₈H₂₀O₂

Color and Shape: White To Light Beige

Molecular weight: 268.35

Ref: TR-E592800

Equilin

Controlled Product

CAS: 474-86-2

Estrogenic steroid produced in horses; used clinically in HRT

Formula: C₁₈H₂₀O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 268.35 g/mol

Ref: 3D-FE22775

Equilin

CAS: 474-86-2

Purity: 98%

Molecular weight: 268.356

Ref: 10-F979574