CAS 474-87-3

8,9-Dehydroestrone

Description:

8,9-Dehydroestrone is a steroid hormone and a derivative of estrone, which is a form of estrogen. It is characterized by the presence of a double bond between the 8th and 9th carbon atoms in its steroid structure, which distinguishes it from other estrogens. This compound is typically found in various biological systems and can be synthesized in the laboratory. Its molecular formula is C18H22O2, and it has a specific arrangement of functional groups that contribute to its biological activity. 8,9-Dehydroestrone is known to interact with estrogen receptors, influencing various physiological processes, including reproductive functions and bone density regulation. Additionally, it may have implications in certain medical conditions, including hormone-related cancers. As with many steroid compounds, its stability and reactivity can be influenced by environmental factors such as pH and temperature. Overall, 8,9-Dehydroestrone plays a significant role in the study of endocrinology and pharmacology, particularly in understanding estrogenic activity and its effects on human health.

Formula: C₁₈H₂₀O₂

InChI: InChI=1S/C18H20O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,16,19H,2,4,6-9H2,1H3/t16-,18-/m0/s1

InChI key: InChIKey=OUGSRCWSHMWPQE-WMZOPIPTSA-N

SMILES: C[C@@]12[C@](C3=C(C=4C(CC3)=CC(O)=CC4)CC1)(CCC2=O)[H]

Synonyms:

• 3-Hydroxyestra-1,3,5(10),8-tetraen-17-one
• 8,9-Dehydroestrone
• D8,9-Dehydroestrone
• D8-Dehydroestrone
• D8-Isoequilin
• Δ^8,9-Dehydroestrone
• Δ⁸-Dehydroestrone
• Δ⁸-Isoequilin
• Estra-1,3,5(10),8-tetraen-17-one, 3-hydroxy-
• -Isoequilin
• ,9-Dehydroestrone
• -Dehydroestrone
• Δ 8,9-Dehydro Estrone Q: What is the CAS Number of
• Equilin Impurity 12
• a8,9-Dehydro Estrone
• 3-Hydroxy-estra-1,3,5(10),8-tetraen-17-one
• Δ 8,9-Dehydro EstroneQ: What is
• Δ 8,9-Dehydro Estrone
• Delta-8,9-Dehydro Estrone
• Estrone 8(9)-Dehydro Impurity
• Δ 8,9-Dehydro Estrone Q: What is the storage condition of
• Δ 8,9-Dehydro Estrone Q: What are the applications of
• 8-Isoequilin

8,9-Dehydroestrone

CAS: 474-87-3

Formula: C₁₈H₂₀O₂

Molecular weight: 268.36

Ref: 4Z-E-1134

∆8,9-Dehydro Estrone

Controlled Product

CAS: 474-87-3

Formula: C₁₈H₂₀O₂

Color and Shape: Off-White To Light Beige

Molecular weight: 268.35

Ref: TR-D229640

∆8,9-Dehydro Estrone-d4

Controlled Product

CAS: 474-87-3

Formula: C₁₈D₄H₁₆O₂

Color and Shape: Neat

Molecular weight: 272.375

Ref: TR-D229642

8,9-Dehydroestrone

Controlled Product

CAS: 474-87-3

8,9-Dehydroestrone is a steroidal sex hormone that is synthesized in the ovaries and adrenal glands. It is a naturally occurring metabolite of estradiol and estrone sulfate. 8,9-Dehydroestrone has been shown to have neuroprotective effects in rat liver microsomes. This effect may be due to its ability to inhibit neuronal death by blocking the activation of caspase-3, an enzyme involved in apoptosis. 8,9-Dehydroestrone also has a role as an estrogen conjugate that can be used for pharmaceutical preparations in women.

Formula: C₁₈H₂₀O₂

Purity: Min. 95%

Molecular weight: 268.35 g/mol

Ref: 3D-FD20911

δ-8,9-Dehydro Estrone

CAS: 474-87-3

Formula: C₁₈H₂₀O₂

Molecular weight: 268.3

Ref: ST-EA-CP-E30006