CAS 4746-61-6

2-hydroxy-N-phenylacetamide

Description:

2-Hydroxy-N-phenylacetamide, also known as paracetamol or acetaminophen, is an organic compound with the molecular formula C8H9NO2. It is characterized by its white crystalline appearance and is soluble in water, alcohol, and ether. This compound features a hydroxyl group (-OH) and an acetamide group, which contribute to its pharmacological properties. Paracetamol is widely recognized for its analgesic (pain-relieving) and antipyretic (fever-reducing) effects, making it a common over-the-counter medication. It works primarily by inhibiting the enzyme cyclooxygenase (COX), leading to a decrease in the synthesis of prostaglandins, which are mediators of pain and inflammation. While generally safe when used as directed, excessive doses can lead to hepatotoxicity, highlighting the importance of adhering to recommended dosages. Paracetamol is often used in combination with other medications to enhance its therapeutic effects and is a staple in pain management protocols. Its relatively low toxicity and effectiveness have made it a widely used analgesic globally.

Formula: C₈H₉NO₂

InChI: InChI=1/C8H9NO2/c10-6-8(11)9-7-4-2-1-3-5-7/h1-5,10H,6H2,(H,9,11)

InChI key: InChIKey=PJFNNMFXEVADGK-UHFFFAOYSA-N

SMILES: N(C(CO)=O)C1=CC=CC=C1

Synonyms:

• 2-Hydroxyacetanilide
• Glycolanilide
• Glycolanilide (8CI)
• Glycolic acid anilide
• N-Phenylglycolamide
• NSC 99271
• acetamide, 2-hydroxy-N-phenyl-
• 2-Hydroxy-N-phenylacetamide
• 2-Hydroxy-N-phenylacetamide
• Diclofenac Sodium Impurity 32
• Diclofenac sodium impurity 1
• Cetirizine Impurity 52
• N-Phenyl-2-hydroxyacetamide
• Hydroxyacetylaminobenzene

2-Hydroxy-N-phenylacetamide

CAS: 4746-61-6

Formula: C₈H₉NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 151.1626

Ref: IN-DA00DGUF

2-Hydroxy-N-phenylacetamide

CAS: 4746-61-6

2-Hydroxy-N-phenylacetamide

Purity: 97%

Ref: 54-OR1041729

2-Hydroxy-N-phenylacetamide

CAS: 4746-61-6

Formula: C₈H₉NO₂

Purity: 97%

Molecular weight: 151.165

Ref: 10-F544670

2-Hydroxy-N-phenylacetamide

CAS: 4746-61-6

2-Hydroxy-N-phenylacetamide is a phosphoric acid that is an amide. It can be synthesized by reacting phenylacetic acid with 2-chloroethanol in the presence of sodium hydroxide and phosphoric acid. This chemical compound has electrocardiographic activity and is used as a synthon to create other drugs, such as inorganic acids, supramolecular complexes, and intermolecular hydrogen bonding compounds. 2-Hydroxy-N-phenylacetamide has been shown to lower blood pressure in clinical studies. It also prevents the formation of methemoglobin caused by exposure to nitrites or nitrates and has been shown to be effective against carboxylate ions such as potassium ion (K+).

Formula: C₈H₉NO₂

Purity: Min. 95%

Molecular weight: 151.16 g/mol

Ref: 3D-EAA74661

2-Hydroxy-N-phenylacetamide

CAS: 4746-61-6

Formula: C₈H₉NO₂

Molecular weight: 151.17

Ref: ST-EA-CP-D20044