CAS: 474645-27-7 - Monomethyl Auristatin E

Formula: C₃₉H₆₇N₅O₇

InChI: InChI=1S/C39H67N5O7/c1-13-25(6)34(43(10)39(49)33(24(4)5)42-38(48)32(40-9)23(2)3)30(50-11)22-31(45)44-21-17-20-29(44)36(51-12)26(7)37(47)41-27(8)35(46)28-18-15-14-16-19-28/h14-16,18-19,23-27,29-30,32-36,40,46H,13,17,20-22H2,1-12H3,(H,41,47)(H,42,48)/t25-,26+,27+,29-,30+,32-,33-,34-,35+,36+/m0/s1

InChI key: InChIKey=DASWEROEPLKSEI-UIJRFTGLSA-N

SMILES: O=C(NC(C(=O)N(C)C(C(OC)CC(=O)N1CCCC1C(OC)C(C(=O)NC(C)C(O)C=2C=CC=CC2)C)C(C)CC)C(C)C)C(NC)C(C)C

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Valinamide, N-methyl-<smallcap>L</span>-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-
• MMAE toxin
• Mmae
• Monomethylauristatin E
• Monomethylauristatin norephedrine
• N-Methyl-<span class="text-smallcaps">L</smallcap>-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-<smallcap>L</span>-valinamide
• Toxin MMAE

Monomethylauristatin E

CAS: 474645-27-7

• Formula: C₃₉H₆₇N₅O₇
• Color and Shape: Off-White Solid
• Molecular weight: 717.99

Monomethylauristatin E-d8

CAS: 2070009-72-0 474645-27-7

• Formula: C₃₉H₅₉D₈N₅O₇
• Color and Shape: White To Off-White Solid
• Molecular weight: 726.04

Monomethyl auristatin E

CAS: 474645-27-7

Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization …

• Formula: C₃₉H₆₇N₅O₇
• Purity: 99.47%
• Color and Shape: Solid
• Molecular weight: 717.98

MMAE

CAS: 474645-27-7

Applications MMAE is an effective and synthetic cytotoxic analog of Dolastatin 10 which is a …

• Formula: C₃₉H₆₇N₅O₇
• Color and Shape: Neat
• Molecular weight: 717.98

Monomethyl auristatin E

CAS: 474645-27-7

Synthetic analog of dolastatin 10; cytotoxic; inhibits tubulin polymerization

• Formula: C₃₉H₆₇N₅O₇
• Purity: Min. 98 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 717.98 g/mol