CAS 474922-26-4

DSPE-PEG 2000 Amine

Description:

DSPE-PEG 2000 Amine, with the CAS number 474922-26-4, is a synthetic amphiphilic compound commonly used in bioconjugation and drug delivery applications. It consists of a hydrophobic di-stearyl phosphatidylethanolamine (DSPE) moiety linked to a hydrophilic polyethylene glycol (PEG) chain, specifically with a molecular weight of approximately 2000 daltons, and an amine functional group. This structure imparts unique characteristics, such as enhanced solubility in aqueous environments and the ability to form stable lipid bilayers or micelles. The amine group allows for further functionalization, enabling the attachment of various biomolecules, such as peptides, proteins, or nucleic acids, facilitating targeted delivery systems. DSPE-PEG 2000 Amine is particularly valued in the formulation of liposomes and nanoparticles, improving their circulation time in biological systems and reducing immunogenicity. Additionally, its biocompatibility and non-toxic nature make it suitable for pharmaceutical applications, including gene therapy and vaccine development. Overall, this compound plays a crucial role in advancing nanomedicine and drug delivery technologies.

Formula: (C₂H₄O)nC₄₄H₈₇N₂O₁₀P·H₃N

InChI: InChI=1S/C46H91N2O11P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-44(49)56-41-43(42-58-60(52,53)57-38-36-48-46(51)55-40-39-54-37-35-47)59-45(50)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h43H,3-42,47H2,1-2H3,(H,48,51)(H,52,53)

InChI key: InChIKey=BBJPYLDHKQBAQS-UHFFFAOYSA-N

SMILES: C(COP(OCCNC(OCCOCCN)=O)(=O)O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.N

Synonyms:

• DSPE-PEG 2000NH2 ammonium salt
• Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-(2-aminoethoxy)-, ammonium salt (1:1)
• Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-(2-aminoethoxy)-, ammonium salt
• DSPE-PEG 2000 Amine
• DSPE-PEG Amine
• DSPE-PEG-2K-Amine
• DSPE-PEG2000-NH2
• DSPE-PEG-NH2
• DSPE-PEG-NH2 ISO 9001：2015 REACH
• 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[aMino(polyethylene glycol)-2000] (aMMoniuM salt)
• 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[AMINO(POLYETHYLENE GLYCOL)-2000] (AMMONIUM SALT);DSPE-PEG(2000) AMINE

DSPE-PEG(2000)-Amine Ammonium Salt

CAS: 474922-26-4

Color and Shape: White to Light yellow powder to crystal

Ref: 3B-D6011

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (ammonium salt)

CAS: 474922-26-4

Formula: C₄₆H₉₄N₃O₁₁P

Color and Shape: Solid

Molecular weight: 896.2258

Ref: IN-DA00DHPX

DSPE-PEG-NH2 Ammonium Salt

CAS: 474922-26-4

DSPE-PEG-NH2 Ammonium Salt

Purity: average Mw2000

Ref: 54-OR1025309

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol) 2000] (ammonium salt)

CAS: 474922-26-4

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol) 2000] (ammonium salt) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol) 2000] (ammonium salt) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: (C₂H₄O)nC₄₄H₈₇N₂O₁₀P•H₃N

Purity: Min. 95%

Color and Shape: White Powder

Ref: 3D-FD157101