CAS 474922-82-2

Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxotetradecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphapentacos-1-yl]-ω-methoxy-, ammonium salt (1:1)

Description:

Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxotetradecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphapentacos-1-yl]-ω-methoxy-, ammonium salt (1:1), identified by CAS number 474922-82-2, is a complex amphiphilic compound characterized by its polyether backbone and functionalized phosphonium groups. This substance exhibits surfactant properties, making it useful in various applications, including drug delivery systems and as an emulsifying agent. Its structure includes multiple oxyethylene units, which contribute to its solubility in water and ability to form micelles. The presence of hydroxy and oxido groups enhances its reactivity and potential for interaction with biological membranes. Additionally, the long hydrophobic alkyl chain (derived from tetradecanoic acid) provides a lipophilic character, facilitating the incorporation of hydrophobic drugs. The ammonium salt form indicates that it is likely to be positively charged in solution, which can influence its interaction with negatively charged biological entities. Overall, this compound's unique structural features enable it to play a significant role in pharmaceutical and biochemical applications.

Formula: (C₂H₄O)nC₃₅H₆₈NO₁₀P·H₃N

InChI: InChI=1S/C37H72NO11P/c1-4-6-8-10-12-14-16-18-20-22-24-26-35(39)46-32-34(33-48-50(42,43)47-29-28-38-37(41)45-31-30-44-3)49-36(40)27-25-23-21-19-17-15-13-11-9-7-5-2/h34H,4-33H2,1-3H3,(H,38,41)(H,42,43)

InChI key: InChIKey=SQPXBATXPJRFFE-UHFFFAOYSA-N

SMILES: C(COP(OCCNC(OCCOC)=O)(=O)O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.N

Synonyms:

• PEG DMG 2000
• 14:0 PEG 2000 PE
• Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxotetradecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphapentacos-1-yl]-ω-methoxy-, ammonium salt (1:1)
• 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium salt
• Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxotetradecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphapentacos-1-yl]-ω-methoxy-, ammonium salt

14:0 PEG2000 PE

CAS: 474922-82-2

14:0 PEG2000 PE (DMPE-PEG2000) is a polyethylene glycol (PEG)-phospholipid coupling that prevents vesicle aggregation in the preparation of vesicle formulations

Formula: (C₂H₄O)nC₃₅H₆₈NO₁₀P·NH₃

Color and Shape: Solid

Molecular weight: 350(Average)

Ref: TM-T74305

DMPE-MPEG-2000, ammonium salt

CAS: 474922-82-2

Formula: (C2H4O)nC35H68NO10P.H3N

Purity: >95%

Color and Shape: White Powder

Ref: 48-38-6041