CAS 475-31-0

Glycocholic acid

Description:

Glycocholic acid is a bile acid derivative formed from the conjugation of cholic acid with glycine. It is a key component of bile, playing a crucial role in the emulsification and absorption of dietary fats and fat-soluble vitamins in the intestine. Glycocholic acid is characterized by its amphipathic nature, possessing both hydrophilic and hydrophobic regions, which facilitates its function as a surfactant. The molecular structure includes a steroid backbone with hydroxyl groups that contribute to its solubility in water. Glycocholic acid is typically found in the form of a white to off-white powder and is soluble in water and alcohol but less soluble in non-polar solvents. It has a relatively high melting point and is stable under physiological conditions. In addition to its digestive functions, glycocholic acid is involved in various metabolic processes and can influence cholesterol metabolism. Its CAS number, 475-31-0, is used for identification in chemical databases and regulatory contexts.

Formula: C₂₆H₄₃NO₆

InChI: InChI=1S/C26H43NO6/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33)/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-/m1/s1

InChI key: InChIKey=RFDAIACWWDREDC-FRVQLJSFSA-N

SMILES: O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(NCC(O)=O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]

Synonyms:

• 3α,7α,12α-Trihydroxy-5β-cholan-24-oylglycine
• 3α,7α,12α-Trihydroxy-5β-cholanic acid-24-glycine
• 3α,7α,12α-Trihydroxy-N-(carboxymethyl)-5β-cholan-24-amide
• 5β-Cholan-24-amide, N-(carboxymethyl)-3α,7α,12α-trihydroxy-
• Cholane, glycine deriv.
• Cholylglycine
• Glycine cholate
• Glycine, N-[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-
• Glycine, N-choloyl-
• Glycocholic Acid Free Acid
• Glycocholic acid
• Glycoreductodehydrocholic acid
• Glycylcholic acid
• N-(3-alpha,7-alpha,12-alpha-trihydroxycholan-24-oyl)glycine
• N-(3-α,7-α,12-α-Trihydroxycholan-24-oyl)glycin
• N-(3-α,7-α,12-α-trihydroxycholan-24-oyl)glycine
• N-(3-α,7-α,12-α-trihydroxycholane-24-oyl)glycine
• N-(3-α-7-α-12-α-trihidroxicolan-24-oil)glicina
• N-Choloylglycine
• N-[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]glycine

Cholyglycine

CAS: 475-31-0

Formula: C₂₆H₄₃NO₆

Purity: 95.64%

Color and Shape: Brownish. Solid

Molecular weight: 465.0

Ref: 8R-CL0480

Glycine, N-[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]-

CAS: 475-31-0

Formula: C₂₆H₄₃NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 465.6227

Ref: IN-DA00I8NU

Glycocholic acid

CAS: 475-31-0

Formula: C₂₆H₄₃NO₆·xH₂O

Purity: ≥ 97.0% (dried basis)

Color and Shape: White to off-white powder

Molecular weight: 465.62 (anhydrous basis)

Ref: 7W-GM1948

Glycocholic acid

CAS: 475-31-0

Glycocholic acid

Purity: ≥98%

Molecular weight: 465.62g/mol

Ref: 54-BUP18271

Glycocholic Acid

CAS: 475-31-0

Formula: C₂₆H₄₃NO₆

Color and Shape: White To Off-White Solid

Molecular weight: 465.63

Ref: 4Z-C-577

Glycocholic Acid-d7

CAS: 475-31-0

Formula: C₂₆H₃₆D₇NO₆

Molecular weight: 472.67

Ref: 4Z-C-57199

Glycocholic Acid

CAS: 475-31-0

Color and Shape: Neat

Ref: 86-MM3875.00

Glycocholic acid

CAS: 475-31-0

Glycocholic acid (Glycocholate) is a bile acid with anticancer activity.

Formula: C₂₆H₄₃NO₆

Purity: 99.6% - 99.92%

Color and Shape: Solid

Molecular weight: 465.62

Ref: TM-T2831

Glycocholic Acid-d5

Controlled Product

CAS: 475-31-0

Stability Hygroscopic
Applications The product of conjugation of cholic acid with glycine; chief ingredient of the bile of herbivorous animals. In the weakly alkaline bile fluid glycocholic acid exists as the sodium salt.
References Ho, R., et al.: J. Biol. Chem., 279, 7213 (2004), Pasanen, M., et al.: Eur. J. Clin. Pharmacol., 62, 409 (2006), He, Y., et al.: Drug Metab. Dispos., 36, 1453 (2008),

Formula: C₂₆H₃₈D₅NO₆

Color and Shape: Neat

Molecular weight: 470.65

Ref: TR-G641352

Glycocholic Acid

CAS: 475-31-0

Applications Glycocholic Acid (cas# 475-31-0) is a useful research chemical.

Formula: C₂₆H₄₃NO₆

Color and Shape: Off-White

Molecular weight: 465.62

Ref: TR-G641370

Glycocholic acid

CAS: 475-31-0

Glycocholic acid is a conjugated bile acid, which is derived from the liver synthesis of bile acids conjugated with glycine. Primarily sourced from cholesterol metabolism, glycocholic acid plays an integral role in the emulsification and absorption of dietary fats. Its mode of action involves the reduction of surface tension within the gut, allowing lipids to form micelles, thus facilitating their transport through the intestinal mucosa.

Formula: C₂₆H₄₃NO₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 465.62 g/mol

Ref: 3D-FG16282

Glycocholic Acid-13C2,D4

Controlled Product

CAS: 475-31-0

Formula: C₂C₂₄D₄H₃₉NO₆

Color and Shape: White To Off-White

Molecular weight: 471.633

Ref: TR-G641476