CAS 475-38-7

Naphthazarin

Description:

Naphthazarin, with the CAS number 475-38-7, is a synthetic organic compound belonging to the class of naphthoquinones. It is characterized by its deep red to purple color, which is attributed to its conjugated double bond system that allows for significant light absorption. Naphthazarin is known for its potential applications in various fields, including as a dye and in biological research due to its ability to interact with cellular components. The compound exhibits moderate solubility in organic solvents, while its solubility in water is limited. Naphthazarin is also recognized for its redox properties, allowing it to participate in electron transfer reactions. Additionally, it has been studied for its potential antimicrobial and anticancer activities, although further research is necessary to fully understand its biological effects and mechanisms of action. As with many chemical substances, proper handling and safety precautions are essential due to its potential toxicity and environmental impact.

Formula: C₁₀H₆O₄

InChI: InChI=1/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H

InChI key: InChIKey=RQNVIKXOOKXAJQ-UHFFFAOYSA-N

SMILES: O=C1C=2C(=C(O)C=CC2O)C(=O)C=C1

Synonyms:

• 1,4-Naphthalenedione, 5,8-Dihydroxy-
• 1,4-Naphthoquinone, 5,8-dihydroxy-
• 475-38-7
• 5,8-Dihydroxy-1,4-naphthalenedione
• 5,8-Dihydroxy-1,4-naphthosemiquinone
• 5,8-Dihydroxynaphthalene-1,4-Dione
• 5,8-Dihydroxynaphthoquinone
• NSC 26647
• NSC 344555
• Naphthazarin
• Naphthazarine
• Naphthazarone
• 5,8-dihydroxy-4-naphthoquinone
• 5,8-Dihydroxy-1,4-n
• NAPHTHAZALINE
• 5,8-HYDROXY-1,4-NAPHTHOQUINONE
• 5,8-DIHYDROXY-1,4-NAPHTHOQUINONE, TECH.
• ,8-Dihydroxy-[1,4]naphthoquinone
• 5,8-Dihydroxy-1,4-naphthoquinone,tech.90%
• 2,3-Dihydro-1,4,5,8-naphthalenetetrone
• 5,8-DIHYDROXY-1,4-NAPHTHOQUINONE
• 5,8-dihydroxy-4-naphthalenedione
• ,8-Dihydroxy-1,4-naphthalenedione

5,8-Dihydroxy-1,4-naphthoquinone

CAS: 475-38-7

Formula: C₁₀H₆O₄

Purity: >85.0%(T)(HPLC)

Color and Shape: Dark red to Brown powder to crystaline

Molecular weight: 190.15

Ref: 3B-D2070

5,8-Dihydroxynaphthalene-1,4-dione

CAS: 475-38-7

Formula: C₁₀H₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 190.1522

Ref: IN-DA003MB0

Naphthazarin

CAS: 475-38-7

Naphthazarin

Purity: ≥95%

Molecular weight: 190.15g/mol

Ref: 54-BUP17255

5,8-Dihydroxy-1,4-naphthoquinone

CAS: 475-38-7

5,8-Dihydroxy-1,4-naphthoquinone

Formula: C₁₀H₆O₄

Purity: tech

Color and Shape: dark red to black powder

Molecular weight: 190.15g/mol

Ref: 54-OR01425

Naphthazarin

CAS: 475-38-7

Naphthazarin triggers apoptosis, has anti-tumor effects via oxidative stress, mitochondrial AIF, microtubule depolymerization, and p53/p21 activation.

Formula: C₁₀H₆O₄

Purity: 98.12% - 99.87%

Color and Shape: Dark Purple To Brown-Black Powder

Molecular weight: 190.15

Ref: TM-T8678

5,8-DIHYDROXY-1,4-NAPHTHOQUINONE

CAS: 475-38-7

Purity: 98%

Molecular weight: 190.154007

Ref: 10-F827779

5,8-Dihydroxy-1,4-naphthoquinone

CAS: 475-38-7

5,8-Dihydroxy-1,4-naphthoquinone is a natural compound that is found in the bark of "Nothofagus" species. It has been shown to inhibit the transcriptional activity of NF-κB and AP-1 through its ability to bind to the response element in these promoters. 5,8-Dihydroxy-1,4-naphthoquinone has been shown to be cytotoxic against HL60 cells in vitro. This cytotoxicity may be due to its ability to cause an increase in cytosolic Ca2+ levels by inhibiting the mitochondrial ATPase enzyme. 5,8-Dihydroxy-1,4-naphthoquinone has also been shown to induce apoptosis in fetal bovine retinal cells and neuronal death in rat cortical neurons. It is thought that this drug may have anticancer properties because it triggers DNA damage and inhibits cell proliferation.

Formula: C₁₀H₆O₄

Purity: Min 85%

Molecular weight: 190.15 g/mol

Ref: 3D-FD30188