CAS 475-80-9

Aristolochic acid II

Description:

Aristolochic acid II is a naturally occurring compound derived from plants in the Aristolochiaceae family, particularly from the genus Aristolochia. It is characterized by its chemical structure, which includes a bicyclic aromatic system and a carboxylic acid functional group. This compound is known for its potent biological activity, including its role as a nephrotoxin and potential carcinogen, which has raised significant health concerns. Aristolochic acid II has been implicated in cases of aristolochic acid nephropathy, a condition associated with kidney damage and urinary tract cancers. The substance exhibits a low solubility in water but is more soluble in organic solvents, which influences its bioavailability and toxicity. Due to its adverse health effects, the use of Aristolochia species in traditional medicine has been discouraged in many regions. Regulatory agencies have issued warnings regarding its consumption, emphasizing the need for caution and awareness of its potential risks. Overall, Aristolochic acid II serves as a critical example of the intersection between natural products and public health.

Formula: C₁₆H₉NO₆

InChI: InChI=1S/C16H9NO6/c18-16(19)10-6-12-15(23-7-22-12)14-9-4-2-1-3-8(9)5-11(13(10)14)17(20)21/h1-6H,7H2,(H,18,19)

InChI key: InChIKey=MEEXETVZNQYRSP-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C2C(=C3C(=C1)OCO3)C=4C(C=C2N(=O)=O)=CC=CC4

Synonyms:

• 3,4-(Methylenedioxy)-10-nitrophenanthrene-1-carboxylic acid
• 6-Nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid
• Aristolochic acid B
• Brn 0329754
• Ccris 6497
• Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 6-nitro-
• Aristolochic acid II

7-HYDROXYARISTOLOCHIC ACID A

CAS: 475-80-9

Formula: C₁₆H₉NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 311.2458

Ref: IN-DA00D8TY

Aristolochic acid B

CAS: 475-80-9

Aristolochic acid B

Purity: ≥98%

Molecular weight: 311.25g/mol

Ref: 54-BUP03460

Aristolochic acid C

CAS: 475-80-9

Formula: C₁₆H₉NO₇

Molecular weight: 327.25

Ref: 7W-GP1126

Aristolochic Acid B

CAS: 475-80-9

Aristolochic acid II (AAII), one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo,

Formula: C₁₆H₉NO₆

Purity: 95%~99%

Color and Shape: Yellow powder

Molecular weight: 311.249

Ref: BP-BP0193

Aristolochic acid B

CAS: 475-80-9

Aristolochic acid B (Aristolochic Acid II) is a natural product from the Aristolochaceae taxon.Cost-effective and quality-assured.

Formula: C₁₆H₉NO₆

Purity: 99.87% - 99.99%

Color and Shape: Solid

Molecular weight: 311.25

Ref: TM-T7031

Aristolochic acid ii

CAS: 475-80-9

Carboxylic acid with additional oxygen functions

Formula: C₁₆H₉NO₆

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 311.25

Ref: 5G-89566