CAS 475086-01-2

2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide

Description:

2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide, with CAS number 475086-01-2, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyrazine ring and a sulfonamide functional group. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in pharmaceutical research. The presence of the diphenyl and pyrazinyl moieties suggests possible interactions with biological targets, potentially influencing its pharmacological profile. Additionally, the butoxy and methylsulfonyl groups may enhance its stability and solubility in biological systems. As a result, this compound may be investigated for its therapeutic applications, particularly in areas related to oncology or neuropharmacology, although specific biological activities would require empirical studies to elucidate its mechanism of action and efficacy. Overall, the structural features of this compound indicate a promising candidate for further research in medicinal chemistry.

Formula: C₂₆H₃₂N₄O₄S

InChI: InChI=1S/C26H32N4O4S/c1-20(2)30(16-10-11-17-34-19-24(31)29-35(3,32)33)23-18-27-25(21-12-6-4-7-13-21)26(28-23)22-14-8-5-9-15-22/h4-9,12-15,18,20H,10-11,16-17,19H2,1-3H3,(H,29,31)

InChI key: InChIKey=QXWZQTURMXZVHJ-UHFFFAOYSA-N

SMILES: N(CCCCOCC(NS(C)(=O)=O)=O)(C(C)C)C=1N=C(C(=NC1)C2=CC=CC=C2)C3=CC=CC=C3

Synonyms:

• 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide
• 2-[4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy]-N-(methylsulfonyl)acetamide
• 2-[4-[(5,6-Diphenylpyrazin-2-yl)-propan-2-ylamino]butoxy]-N-methylsulfonylacetamide
• Acetamide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)-
• Acetamide, 2-[4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)-
• Act 293987
• Ns 304
• Selexipag
• Uptravi
• Slipper
• Selexipag (10mM in DMSO)
• Selexipag(NS-304)
• Selexipag intermediate 1
• 2-[4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamine]butyloxy]-N-(methylsulfonyl)acetamide
• Selexipag intermediate 2
• SELEXIPAG;ACT293987;NS304;NS 304;ACT 293987;ACT-293987
• NS-304;ACT-293987
• Selexipag API
• (2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetate

Selexipag

CAS: 475086-01-2

Formula: C₂₆H₃₂N₄O₄S

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 496.63

Ref: 3B-E1613

2-(4-((5,6-Diphenylpyrazin-2-Yl)(Isopropyl)Amino)Butoxy)-N-(Methylsulfonyl)Acetamide

CAS: 475086-01-2

2-(4-((5,6-Diphenylpyrazin-2-Yl)(Isopropyl)Amino)Butoxy)-N-(Methylsulfonyl)Acetamide

Formula: C₂₆H₃₂N₄O₄S

Purity: 98%

Molecular weight: 496.62

Ref: 54-OR1023003

NS-304

CAS: 475086-01-2

Formula: C₂₆H₃₂N₄O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 496.6217

Ref: IN-DA00DAAW

Selexipag

CAS: 475086-01-2

Formula: C₂₆H₃₂N₄O₄S

Color and Shape: Off-White Solid

Molecular weight: 496.63

Ref: 4Z-S-101001

Selexipag

CAS: 475086-01-2

Selexipag

Formula: C₂₆H₃₂N₄O₄S

Purity: ≥98%

Molecular weight: 496.62

Ref: 54-BUP16217

Selexipag

CAS: 475086-01-2

Color and Shape: Neat

Ref: 86-MM3799.00

Selexipag

CAS: 475086-01-2

2-(4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide

Formula: C₂₆H₃₂N₄O₄S

Purity: 98%

Molecular weight: 496.62

Ref: IN-DG427469

Selexipag-d8

CAS: 475086-01-2

Formula: C₂₆H₂₄D₈N₄O₄S

Molecular weight: 504.67

Ref: 4Z-S-101009

Selexipag

CAS: 475086-01-2

Selexipag (ACT-293987, NS-304) is a drug for PAH that dilates pulmonary vessels.

Formula: C₂₆H₃₂N₄O₄S

Purity: 99.98% - >99.99%

Color and Shape: White Solid

Molecular weight: 496.62

Ref: TM-T3216

Selexipag

CAS: 475086-01-2

Formula: C₂₆H₃₂N₄O₄S

Molecular weight: 496.63

Ref: ST-EA-CP-S20000

Selexipag

CAS: 475086-01-2

Non-prostanoid IP receptor agonist

Formula: C₂₆H₃₂N₄O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 496.60 g/mol

Ref: 3D-FD106425

Selexipag

CAS: 475086-01-2

Formula: C₂₆H₃₂N₄O₄S

Molecular weight: 496.6

Ref: BE-RMCS062000

Selexipag

Controlled Product

CAS: 475086-01-2

Applications Selexipag is an orally available, highly selective, long-acting prostacyclin (IP) receptor agonist prodrug. It is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.
References Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);

Formula: C₂₆H₃₂N₄O₄S

Color and Shape: Neat

Molecular weight: 496.62

Ref: TR-S253150

Selexipag-d10

Controlled Product

CAS: 475086-01-2

Formula: C₂₆D₁₀H₂₂N₄O₄S

Color and Shape: Neat

Molecular weight: 506.683

Ref: TR-S253153