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CAS 475250-46-5

:

4-(Trifluoromethyl)benzylboronic acid pinacol ester

Description:
4-(Trifluoromethyl)benzylboronic acid pinacol ester is an organoboron compound characterized by the presence of a boronic acid functional group esterified with pinacol and a trifluoromethyl-substituted benzyl moiety. This compound typically exhibits a white to off-white solid appearance and is soluble in organic solvents such as dichloromethane and tetrahydrofuran. The trifluoromethyl group enhances its lipophilicity and can influence its reactivity in various chemical transformations, particularly in cross-coupling reactions, making it valuable in synthetic organic chemistry. The boronic acid functionality allows for the formation of covalent bonds with diols and other nucleophiles, facilitating the development of complex molecular architectures. Additionally, the pinacol ester form provides stability and ease of handling, while also serving as a precursor for the regeneration of the corresponding boronic acid under appropriate conditions. Overall, this compound is significant in medicinal chemistry and materials science due to its unique reactivity and functional properties.
Formula:C14H20BF3O3
Synonyms:
  • 2-(4-(Trifluoromethyl)benzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 4,4,5,5-TetraMethyl-2-(4-(trifluoroMethyl)benzyl)-1,3,2-dioxaborolane
  • 4-(Trifluoromethyl)benzylboronic acid pinacol ester ISO 9001：2015 REACH
  • 3-hydroxy-2,3-dimethylbutan-2-yl hydrogen 4-(trifluoromethyl)benzylboronate
  • 4-(Trifluoromethyl)benzylboronic acid picol ester
  • 4-(trifluoromethyl)benzylboronic acid pinacol ester
  • 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[[4-(trifluoromethyl)phenyl]methyl]-
  • 4-(Trifluoromethyl)benzylboron
  • 4,4,5,5-tetramethyl-2-[[4-(trifluoromethyl)phenyl]methyl]-1,3,2-dioxaborolane
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