CAS 47562-08-3

Lorajmine

Description:

Lorajmine, identified by its CAS number 47562-08-3, is a chemical compound that belongs to the class of pharmaceuticals known as antihistamines. It is primarily used for its antihistaminic properties, which help alleviate allergic reactions by blocking the action of histamine, a substance in the body that causes allergic symptoms. Lorajmine is characterized by its ability to cross the blood-brain barrier, which may lead to sedative effects, making it useful in treating conditions such as insomnia or anxiety in addition to allergies. The compound typically exhibits moderate solubility in organic solvents and may have varying stability depending on environmental conditions such as pH and temperature. As with many pharmaceuticals, the safety profile, potential side effects, and interactions with other medications are important considerations in its use. Overall, Lorajmine represents a significant tool in the management of allergic conditions and related disorders, although its specific pharmacokinetics and dynamics would require further detailed study for comprehensive understanding.

Formula: C₂₂H₂₇ClN₂O₃

InChI: InChI=1/C22H27ClN2O3/c1-3-11-12-8-15-19-22(13-6-4-5-7-14(13)24(19)2)9-16(25(15)21(11)27)18(12)20(22)28-17(26)10-23/h4-7,11-12,15-16,18-21,27H,3,8-10H2,1-2H3/t11-,12-,15-,16-,18?,19-,20+,21+,22+/m0/s1

InChI key: InChIKey=LAHDERDHXJFFJU-MPTFIETCSA-N

SMILES: O(C(CCl)=O)[C@H]1C23[C@]([C@]4(N5[C@@](C2)(C1C(C4)[C@H](CC)[C@H]5O)[H])[H])(N(C)C=6C3=CC=CC6)[H]

Synonyms:

• Ajmalan-17,21-diol, 17-(2-chloroacetate), (17R,21α)-
• 17-(Monochloroacetyl)ajmaline
• Ritmos-Elle
• 17-(Chloroacetyl)ajmaline
• Ajmalan-17,21-diol, 17-(chloroacetate), (17R,21α)-
• Lorajmina [inn-spanish]
• Einecs 256-322-9
• lorajmine
• 17-monochloroacetylajmaline
• Lorajmina
• Lorajmine [inn]
• Lorajminum

Lorajmine

CAS: 47562-08-3

Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.

Formula: C₂₂H₂₇ClN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 402.91

Ref: TM-T25755