CAS 476-28-8

Lycorine

Description:

Lycorine is a naturally occurring alkaloid primarily extracted from plants in the Amaryllidaceae family, particularly from the genus Lycoris. It is known for its structural complexity, featuring a phenanthridine skeleton. Lycorine exhibits a range of biological activities, including antiviral, antibacterial, and anticancer properties, making it a subject of interest in pharmacological research. The compound has been shown to inhibit protein synthesis, which contributes to its potential therapeutic effects. Lycorine is typically found in various plant parts, including bulbs and leaves, and is often studied for its effects on cellular processes. Its solubility characteristics vary, and it is generally soluble in organic solvents while being less soluble in water. Due to its bioactive nature, lycorine is also associated with toxicity at higher concentrations, necessitating careful handling and dosage considerations in research and potential medicinal applications. Overall, lycorine represents a significant compound in natural product chemistry with promising implications in drug development.

Formula: C₁₆H₁₇NO₄

InChI: InChI=1S/C16H17NO4/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19/h3-5,11,14-16,18-19H,1-2,6-7H2/t11-,14-,15+,16+/m0/s1

InChI key: InChIKey=XGVJWXAYKUHDOO-DANNLKNASA-N

SMILES: O[C@H]1[C@@]2([C@@]3(N(CC=4C2=CC5=C(C4)OCO5)CCC3=C[C@@H]1O)[H])[H]

Synonyms:

• (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol
• 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, (1S,2S,12bS,12cS)-
• 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, [1S-(1α,2β,12bβ,12cα)]-
• 3,3a-Didehydrolycoran-1alpha,2beta-diol
• 3,3a-Didehydrolycoran-1α,2β-diol
• 3,4-Didehydro-11,12-[methylenebis(oxy)]galanthan-1α,2β-diol
• Amarylline
• Galanthan-1,2-diol, 3,12-didehydro-9,10-(methylenebis(oxy))-, (1-alpha,2-beta)- (9CI)
• Galanthan-1,2-diol, 3,12-didehydro-9,10-[methylenebis(oxy)]-, (1α,2β)-
• Galanthidine
• Licorine
• Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-
• Lycoran-1alpha,2beta-diol, 3,3a-didehydro- (8CI)
• Lycoran-1α,2β-diol, 3,3a-didehydro-
• NSC 683873
• Narcissin
• Narcissine

Lycorine

CAS: 476-28-8

Formula: C₁₆H₁₇NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 287.32

Ref: 3B-L0445

(1S,2S,3A1S,12Bs)-2,3A1,4,5,7,12B-Hexahydro-1H-[1,3]Dioxolo[4,5-J]Pyrrolo[3,2,1-De]Phenanthridine-1,2-Diol

CAS: 476-28-8

(1S,2S,3A1S,12Bs)-2,3A1,4,5,7,12B-Hexahydro-1H-[1,3]Dioxolo[4,5-J]Pyrrolo[3,2,1-De]Phenanthridine-1,2-Diol

Purity: ≥98%

Molecular weight: 287.31g/mol

Ref: 54-OR1025693

Lycorine

CAS: 476-28-8

Lycorine

Purity: ≥98%

Molecular weight: 287.31g/mol

Ref: 54-BUP13697

Lycorine

CAS: 476-28-8

Formula: C₁₆H₁₇NO₄

Purity: ≥ 98.0%

Color and Shape: White to light-yellow powder

Molecular weight: 287.31

Ref: 7W-GP9688

Lycorine

CAS: 476-28-8

Formula: C₁₆H₁₇NO₄

Purity: 95%~99%

Molecular weight: 287.315

Ref: BP-BP0904

Lycorine

CAS: 476-28-8

Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.

Formula: C₁₆H₁₇NO₄

Purity: 98.60% - 99.95%

Color and Shape: Solid

Molecular weight: 287.31

Ref: TM-T3324

(-)-Lycorine

CAS: 476-28-8

(-)-Lycorine is a naturally occurring alkaloid, which is extracted from plants belonging to the Amaryllidaceae family. This compound is primarily sourced from various species such as the Narcissus and Lycoris genera. It is known for its significant biological activities, serving as a potent inhibitor of protein synthesis. (-)-Lycorine exerts its effects by interfering with the elongation step of translation, thus blocking the proliferation of various cell types.

Formula: C₁₆H₁₇NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 287.31 g/mol

Ref: 3D-FL65705

LYCORINE

CAS: 476-28-8

Purity: ≥98%

Molecular weight: 287.3150024

Ref: 10-F859161