CAS 476371-80-9

1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-(phenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Description:

The chemical substance known as 1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-(phenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, with the CAS number 476371-80-9, is a complex organic compound that features a pyrazolo[3,4-d]pyrimidine core structure. This compound is characterized by the presence of multiple functional groups, including hydroxyl, phosphonyl, and ribofuranosyl moieties, which contribute to its potential biological activity. The presence of the ribofuranosyl group suggests that it may interact with nucleic acids or enzymes involved in nucleotide metabolism. Additionally, the phenylmethyl substituent may enhance its lipophilicity, potentially influencing its pharmacokinetic properties. The compound's intricate structure indicates that it may have applications in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways. Its unique combination of functionalities may also allow for interactions with various biological targets, making it a subject of interest for further research in drug design and development.

Formula: C₁₇H₂₂N₅O₁₃P₃

InChI: InChI=1S/C17H22N5O13P3/c18-15-12-10(6-9-4-2-1-3-5-9)21-22(16(12)20-8-19-15)17-14(24)13(23)11(33-17)7-32-37(28,29)35-38(30,31)34-36(25,26)27/h1-5,8,11,13-14,17,23-24H,6-7H2,(H,28,29)(H,30,31)(H2,18,19,20)(H2,25,26,27)/t11-,13-,14-,17-/m1/s1

InChI key: InChIKey=ZJFXXUXEJRUXPF-LSCFUAHRSA-N

SMILES: O[C@H]1[C@H](N2C=3C(C(CC4=CC=CC=C4)=N2)=C(N)N=CN3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O

Synonyms:

• 1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-(phenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-(phenylmethyl)-

4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranosyl 5’-triphosphate

CAS: 476371-80-9

Ref: 7W-GN6299

4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranosyl 5'-triphosphate

CAS: 476371-80-9

4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1bDribofuranosyl 5'-triphosphate is a novel nucleoside analog that has been shown to have antiviral and anticancer activities. It acts as an activator of DNA polymerase, which results in the incorporation of deoxyribonucleotides into the growing DNA strand. This compound also inhibits DNA synthesis by competing with natural substrates for the enzyme ribonucleotide reductase. 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1bDribofuranosyl 5'-triphosphate is a modified nucleoside that has been synthesized by replacing the phosphate group with diphosphate group on the sugar moiety. The chemical name for this compound is 4-(2'-deoxy-β

Formula: C₁₇H₂₂N₅O₁₃P₃

Purity: Min. 95%

Molecular weight: 597.3 g/mol

Ref: 3D-NA16508