CAS 477-17-8

(+)-Hippeastrine

Description:

(+)-Hippeastrine, with the CAS number 477-17-8, is an alkaloid derived from various plant species, particularly those in the Amaryllidaceae family. This compound is characterized by its structural features, which include a bicyclic framework typical of many alkaloids. It exhibits a chiral center, contributing to its optical activity, as indicated by the "(+)" designation, which refers to its dextrorotatory nature. (+)-Hippeastrine is known for its potential pharmacological properties, including effects on the central nervous system and possible applications in medicinal chemistry. The compound may interact with various biological targets, although detailed studies on its mechanism of action and therapeutic efficacy are still ongoing. In terms of physical properties, it is typically a solid at room temperature and may have specific solubility characteristics in organic solvents. As with many alkaloids, safety and toxicity profiles are important considerations for its use in research and potential therapeutic applications.

Formula: C₁₇H₁₇NO₅

InChI: InChI=1S/C17H17NO5/c1-18-3-2-8-4-11(19)16-14(15(8)18)9-5-12-13(22-7-21-12)6-10(9)17(20)23-16/h4-6,11,14-16,19H,2-3,7H2,1H3/t11-,14-,15+,16+/m0/s1

InChI key: InChIKey=DGQPIOQRPAGNGB-DANNLKNASA-N

SMILES: CN1[C@]2([C@@]3(C=4C(=CC5=C(C4)OCO5)C(=O)O[C@@]3([C@@H](O)C=C2CC1)[H])[H])[H]

Synonyms:

• Trispherine
• (5S,5aS,12bS,12cS)-2,3,5,5a,12b,12c-Hexahydro-5-hydroxy-1-methyl[1,3]dioxolo[6,7][2]benzopyrano[3,4-g]indol-7(1H)-one
• [1,3]Dioxolo[6,7][2]benzopyrano[3,4-g]indol-7(1H)-one, 2,3,5,5a,12b,12c-hexahydro-5-hydroxy-1-methyl-, (5S,5aS,12bS,12cS)-
• Hippeastrine
• Lycorenan-7-one, 5-hydroxy-1-methyl-9,10-[methylenebis(oxy)]-, (5α)-

Hippeastrine

CAS: 477-17-8

Hippeastrine is an alkaloid that inhibits Top I dose-dependently with a 7.25 μg/mL IC50 and has anticancer properties.

Formula: C₁₇H₁₇NO₅

Color and Shape: Solid

Molecular weight: 315.32

Ref: TM-T75655