CAS 477-43-0

(-)-Dehydrocostus lactone

Description:

(-)-Dehydrocostus lactone, with the CAS number 477-43-0, is a naturally occurring sesquiterpene lactone primarily derived from the roots of the plant Saussurea costus, commonly known as costus root. This compound is characterized by its unique bicyclic structure, which contributes to its distinctive aroma and flavor profile. It exhibits a yellowish to brownish color and is known for its bitter taste. (-)-Dehydrocostus lactone has garnered interest in various fields, including traditional medicine, due to its potential anti-inflammatory, antimicrobial, and anticancer properties. Additionally, it is utilized in the fragrance and flavor industry for its pleasant scent. The compound is soluble in organic solvents but has limited solubility in water. Its stability can be influenced by environmental factors such as light and temperature. As with many natural products, further research is ongoing to fully elucidate its biological activities and potential applications in pharmaceuticals and other industries.

Formula: C₁₅H₁₈O₂

InChI: InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h11-14H,1-7H2/t11-,12-,13-,14-/m0/s1

InChI key: InChIKey=NETSQGRTUNRXEO-XUXIUFHCSA-N

SMILES: C=C1[C@@]2([C@@]3([C@](C(=C)C(=O)O3)(CCC(=C)[C@@]2(CC1)[H])[H])[H])[H]

Synonyms:

• (3aS,6aR,9aR,9bS)-3,6,9-trimethylidenedecahydroazuleno[4,5-b]furan-2(3H)-one
• (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one
• Azuleno[4,5-b]furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS,6aR,9aR,9bS)-
• Azuleno[4,5-b]furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, [3aS-(3aα,6aα,9aα,9bβ)]-
• Costus lactone, dehydro-
• Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one
• Dehydrocostuslactone
• Epiligulyl oxide
• Guaia-4(15),10(14),11(13)-trien-12-oic acid, 6α-hydroxy-, γ-lactone
• (3aS)-3,6,9-Tris(methylene)-2,3,3a,4,5,6,6aβ,7,8,9,9aβ,9bα-dodecahydroazuleno[4,5-b]furan-2-one
• DEHYDROCOSTUNOLIDE
• 3aβ,4,5,6,6aβ,7,8,9,9aβ,9bα-Decahydro-3,6,9-trismethyleneazuleno[4,5-b]furan-2(3H)-one
• Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-
• (3aS,6aβ,9aβ,9bα)-Dodecahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2-one
• tris(methylene)-,(3aS,6aR,9aR,9bS)-

Dehydrocostus Lactone

CAS: 477-43-0

Formula: C₁₅H₁₈O₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 230.31

Ref: 3B-D5366

Azuleno[4,5-b]furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-,(3aS,6aR,9aR,9bS)-

CAS: 477-43-0

Formula: C₁₅H₁₈O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 230.3022

Ref: IN-DA00I8OS

Dehydrocostus lactone

CAS: 477-43-0

Formula: C₁₅H₁₈O₂

Molecular weight: 230.30

Ref: 7W-GL1542

Dehydrocostus Lactone

CAS: 477-43-0

Dehydrocostus Lactone

Purity: ≥98%

Molecular weight: 230.3g/mol

Ref: 54-BUP10572

Dehydrocostus Lactone

CAS: 477-43-0

Dehydrocostus Lactone

Purity: 98%

Molecular weight: 230.3g/mol

Ref: 54-OR1025721

Dehydrocostus Lactone

CAS: 477-43-0

Dehydrocostus lactone(DCL) is exuded from sunflower roots and low DCL concentrations stimulate germination of the root parasite Orobanche cumana.

Formula: C₁₅H₁₈O₂

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 230.307

Ref: BP-BP0461

Dehydrocostus Lactone

CAS: 477-43-0

Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.

Formula: C₁₅H₁₈O₂

Purity: 99.86% - 99.98%

Color and Shape: Solid

Molecular weight: 230.3

Ref: TM-T2833

Dehydrocostus Lactone-d3

CAS: 477-43-0

Formula: C₁₅H₁₅D₃O₂

Molecular weight: 233.33

Ref: 4Z-S-178015

Dehydrocostus Lactone

CAS: 477-43-0

Formula: C₁₅H₁₈O₂

Molecular weight: 230.31

Ref: 4Z-S-178012

Dehydrocostus lactone

CAS: 477-43-0

Lactone

Formula: C₁₅H₁₈O₂

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 230.31

Ref: 5G-89624

Dehydrocostus lactone

CAS: 477-43-0

Dehydrocostus lactone is a sesquiterpene lactone, which is a natural compound extracted from plants, notably from the roots of Saussurea lappa, a plant known for its therapeutic properties. This compound exerts its mode of action primarily through the inhibition of key inflammatory pathways, including the NF-κB pathway. By interfering with these pathways, dehydrocostus lactone can modulate the expression of pro-inflammatory cytokines, thereby exhibiting anti-inflammatory effects.

Formula: C₁₅H₁₈O₂

Purity: Min. 95%

Molecular weight: 230.3 g/mol

Ref: 3D-FD59589

Dehydrocostus Lactone

Controlled Product

CAS: 477-43-0

Applications Dehydrocostus Lactone is a compound known to be a growth regulator in plants. Known to affect cell viability and cell cycle distribution it may be useful in the application towards drug-resistant tumors.
References Joel, D. et al.: Phytochem., 72, 624 (2011); Kretschmer, N. et al.: Planta. Med. 78, 1749 (2012);

Formula: C₁₅H₁₈O₂

Color and Shape: Neat

Molecular weight: 230.30

Ref: TR-D229255