CAS 477-48-5

(-)-Picropodophyllone

Description:

(-)-Picropodophyllone is a naturally occurring lignan compound derived from the plant species Podophyllum peltatum, commonly known as the mayapple. It is characterized by its complex polycyclic structure, which includes a dibenzylbutyrolactone skeleton. This compound exhibits notable biological activities, particularly as an antitumor agent, and has been studied for its potential in cancer therapy due to its ability to inhibit cell proliferation. (-)-Picropodophyllone is also recognized for its role in traditional medicine and has been investigated for its effects on various cellular pathways. The compound is typically found in a crystalline form and is soluble in organic solvents, but its solubility in water is limited. Its chemical properties, including melting point and spectral characteristics, are essential for its identification and analysis in research settings. As with many natural products, the extraction and purification processes are critical for obtaining (-)-Picropodophyllone in a form suitable for pharmacological studies.

Formula: C₂₂H₂₀O₈

InChI: InChI=1S/C22H20O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-19H,8-9H2,1-3H3/t13-,18+,19+/m0/s1

InChI key: InChIKey=ISCQYPPCSYRZOT-MJXNMMHHSA-N

SMILES: O=C1[C@]2([C@@H](C=3C(C(=O)[C@]2(CO1)[H])=CC4=C(C3)OCO4)C5=CC(OC)=C(OC)C(OC)=C5)[H]

Synonyms:

• (-)-Picropodophyllone
• (5aR,8aS,9R)-5a,6,8a,9-Tetrahydro-9-(3,4,5-trimethoxyphenyl)furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione
• Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione, 5a,6,8a,9-tetrahydro-9-(3,4,5-trimethoxyphenyl)-, (5aR,8aS,9R)-
• Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione, 5a,6,8a,9-tetrahydro-9-(3,4,5-trimethoxyphenyl)-, [5aR-(5aα,8aα,9α)]-
• Picropodophyllotoxon
• Picropodophyllotoxone
• furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione, 5a,6,8a,9-tetrahydro-9-(3,4,5-trimethoxyphenyl)-, (5aR,8aS,9R)-

Picropodophyllone

CAS: 477-48-5

Picropodophyllone

Purity: ≥98%

Molecular weight: 412.39g/mol

Ref: 54-BUP07586

Picropodophyllotoxone

CAS: 477-48-5

Formula: C₂₂H₂₀O₈

Purity: ≥ 98.0%

Color and Shape: White to off-white solid

Molecular weight: 412.39

Ref: 7W-GY9269

Picropodophyllotoxone

CAS: 477-48-5

Formula: C₂₂H₂₀O₈

Purity: 95%~99%

Molecular weight: 412.394

Ref: BP-BP4081

Picropodophyllone

CAS: 477-48-5

Picropodophyllone is one of the lignans from the roots of D. aurantiocaulis and D. pleianthum.

Formula: C₂₂H₂₀O₈

Purity: 99.86%

Color and Shape: Solid

Molecular weight: 412.39

Ref: TM-TN2071

Picropodophyllone

CAS: 477-48-5

Picropodophyllone is a naturally occurring podophyllotoxin analog, which is derived primarily from the roots and rhizomes of plants in the Podophyllum genus. This compound exhibits its biological activity by interfering with microtubule assembly and cell division, mechanisms akin to those observed in other lignan-based compounds.

Formula: C₂₂H₂₀O₈

Purity: Min. 95%

Molecular weight: 412.4 g/mol

Ref: 3D-AAA47748