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CAS 477291-09-1

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4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbonyl chloride

Description:
4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbonyl chloride is a synthetic organic compound characterized by its thiazole ring, which is a five-membered heterocyclic structure containing sulfur and nitrogen. This compound features a carbonyl chloride functional group, indicating it is a reactive acyl chloride, which can participate in various chemical reactions, particularly acylation. The presence of a trifluoromethyl group enhances its lipophilicity and may influence its biological activity, making it of interest in medicinal chemistry. The methyl group on the thiazole ring contributes to its overall hydrophobic character. This compound is likely to be a solid at room temperature, with potential applications in pharmaceuticals or agrochemicals due to its unique structural features. Its reactivity as an acyl chloride suggests it can be used in the synthesis of other chemical entities, particularly in the formation of amides or esters. Safety precautions should be taken when handling this compound, as acyl chlorides can be corrosive and may release harmful gases upon reaction with water or alcohols.
Formula:C12H7ClF3NOS
InChI:InChI=1/C12H7ClF3NOS/c1-6-9(10(13)18)19-11(17-6)7-2-4-8(5-3-7)12(14,15)16/h2-5H,1H3
SMILES:Cc1c(C(=O)Cl)sc(c2ccc(cc2)C(F)(F)F)n1
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