CAS 4773-96-0

Mangiferin

Description:

Mangiferin is a naturally occurring polyphenolic compound primarily found in mangoes and various other plants, particularly in the Anacardiaceae family. It is classified as a xanthone glycoside, characterized by its complex structure that includes a xanthone core linked to a glucose moiety. Mangiferin exhibits a range of biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties, making it of interest in pharmacological research. Its chemical formula is C17H17O11, and it has a molecular weight of approximately 433.31 g/mol. Mangiferin is soluble in water and organic solvents, which enhances its bioavailability. The compound has been studied for its potential therapeutic effects, including its role in managing metabolic disorders, cardiovascular diseases, and certain types of cancer. Additionally, mangiferin's safety profile has been evaluated, indicating low toxicity levels in various studies. Overall, mangiferin represents a significant area of interest in natural product chemistry and medicinal research due to its diverse health benefits and applications.

Formula: C₁₉H₁₈O₁₁

InChI: InChI=1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1

InChI key: InChIKey=AEDDIBAIWPIIBD-ZJKJAXBQSA-N

SMILES: OC1=C2C(OC=3C(C2=O)=CC(O)=C(O)C3)=CC(O)=C1[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Synonyms:

• (1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol
• (1xi)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol
• 1,3,6,7-Tetrahydroxyxanthone-C₂-β-<span class="text-smallcaps">D</span>-glucoside
• 1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)hexitol
• 2-C-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-1,3,6,7-tetrahydroxyxanthone
• 2-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one
• 9H-Xanthen-9-one, 2-β-<span class="text-smallcaps">D</span>-glucopyranosyl-1,3,6,7-tetrahydroxy-
• Alpizarin
• Alpizarine
• Aphloiol
• Chinomin
• Chinonin
• Hedysarid
• Mangiferin
• NSC 248870
• Shamimin
• Xanthone-c-glucoside
• 2-β-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one

Mangiferin

CAS: 4773-96-0

Formula: C₁₉H₁₈O₁₁

Molecular weight: 422.34

Ref: ST-EA-CP-M117000

Mangiferin, 98%

CAS: 4773-96-0

Mangiferin is a monosodium salt of mangiferin and has been shown to have DNA-binding activity. It is an activator of the apoptosis pathway and has been shown to inhibit the dinucleotide phosphate (DNP) synthase enzyme, which is involved in nucleotide synthesis. This inhibition prevents cells from making DNA and RNA, leading to cell death. Mangiferin also has hypoglycemic effects in humans due to its ability to inhibit glycolysis. The biological properties of mangiferin are not well understood but it has been shown that it may be detoxified by enzymes such as cytochrome P450 or glutathione S-transferase. Mangiferin also exhibits anti-cancer activities against colorectal adenocarcinoma cells and human breast cancer cells MDA-MB-231. It acts by inhibiting dextran sulfate (DS) uptake, which is an important component for the proliferation of tumor cells.

Formula: C₁₉H₁₈O₁₁

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 422.34 g/mol

Ref: 3D-FM158983