CAS 47747-56-8

Talampicillin

Description:

Talampicillin is a semi-synthetic antibiotic belonging to the penicillin class, specifically designed to combat bacterial infections. It is characterized by its broad-spectrum activity against various Gram-positive and some Gram-negative bacteria. The molecular structure of Talampicillin includes a beta-lactam ring, which is essential for its antibacterial activity, as it inhibits bacterial cell wall synthesis. This compound is typically administered in its salt form to enhance solubility and bioavailability. Talampicillin is often used in clinical settings for treating respiratory tract infections, urinary tract infections, and skin infections, among others. Its pharmacokinetics indicate that it is absorbed well when taken orally, with a relatively short half-life, necessitating multiple doses for effective treatment. As with other antibiotics, the potential for resistance development is a concern, making appropriate use crucial. Side effects may include allergic reactions, gastrointestinal disturbances, and alterations in normal flora. Overall, Talampicillin represents an important tool in the antibiotic arsenal, particularly in the treatment of susceptible bacterial infections.

Formula: C₂₄H₂₃N₃O₆S

InChI: InChI=1S/C24H23N3O6S/c1-24(2)17(22(31)33-23-14-11-7-6-10-13(14)21(30)32-23)27-19(29)16(20(27)34-24)26-18(28)15(25)12-8-4-3-5-9-12/h3-11,15-17,20,23H,25H2,1-2H3,(H,26,28)/t15-,16-,17+,20-,23?/m1/s1

InChI key: InChIKey=SOROUYSPFADXSN-SUWVAFIASA-N

SMILES: C(OC1C=2C(C(=O)O1)=CC=CC2)(=O)[C@@H]3N4[C@@]([C@H](NC([C@H](N)C5=CC=CC=C5)=O)C4=O)(SC3(C)C)[H]

Synonyms:

• 3-Phthalidyl D-2-amino-2-phenylacetamidopenicillanic acid
• Talampicillin
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, [2S-[2α,5α,6β(S*)]]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, (2S,5R,6R)-

Talampicillin

CAS: 47747-56-8

Talampicillin, an Ampicillin ester, yields higher bioavailability upon GI absorption, used for children's urinary infections.

Formula: C₂₄H₂₃N₃O₆S

Color and Shape: Solid

Molecular weight: 481.52

Ref: TM-T34776