CAS 4776-06-1

3,5-Dibromo-2-hydroxy-N-(3-(trifluoromethyl)phenyl)benzamide

Description:

3,5-Dibromo-2-hydroxy-N-(3-(trifluoromethyl)phenyl)benzamide, with the CAS number 4776-06-1, is a chemical compound that features a complex structure characterized by the presence of bromine and trifluoromethyl groups. This compound is classified as an aromatic amide due to the presence of the benzamide functional group, which contributes to its potential biological activity. The dibromo substituents enhance its reactivity and may influence its solubility and stability in various solvents. The hydroxy group provides additional hydrogen bonding capabilities, which can affect its interactions with other molecules. The trifluoromethyl group is known for imparting unique electronic properties, often enhancing lipophilicity and altering the compound's pharmacokinetic profile. Overall, this compound may exhibit interesting properties for applications in pharmaceuticals, agrochemicals, or materials science, although specific biological activities and applications would require further investigation. Safety and handling precautions should be observed due to the presence of halogenated groups, which can pose environmental and health risks.

Formula: C₁₄H₈Br₂F₃NO₂

InChI: InChI=1/C14H8Br2F3NO2/c15-8-5-10(12(21)11(16)6-8)13(22)20-9-3-1-2-7(4-9)14(17,18)19/h1-6,21H,(H,20,22)

InChI key: InChIKey=VYKKDKFTDMVOBU-UHFFFAOYSA-N

SMILES: C(NC1=CC(C(F)(F)F)=CC=C1)(=O)C2=C(O)C(Br)=CC(Br)=C2

Synonyms:

• 3,5-Dibromo-3'-(trifluoromethyl)salicylanilide
• 3,5-Dibromo-alpha,alpha,trifluoro-m-salicylotoluidide
• 3,5-Dibromo-α,α,α-trifluoro-m-salicylotoluidide
• Benzamide, 3,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]-
• Fluorophene
• Fluorosalan
• Fluorsalan
• Flusalan
• NSC 166520
• Vancide FP
• Wr 78550
• m-Salicylotoluidide, 3,5-dibromo-α,α,α-trifluoro-

Fluorosalan

Controlled Product

CAS: 4776-06-1

Applications Fluorosalan is used in pharmacological activity and biological study for identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action in cancer therapy. Anti-bacterial agent used in handwash solutions.
References Miller, S.C., et al.: Biochem. Pharmacol., 79, 1272-1280 (2010);

Formula: C₁₄H₈Br₂F₃NO₂

Color and Shape: Neat

Molecular weight: 439.02

Ref: TR-F595065

Fluorosalan

CAS: 4776-06-1

Fluorosalan is a topical antiseptic, which is a fluorinated salicylamide derivative with bacteriostatic properties. This product is synthesized through the halogenation of salicylamide, a compound known for its antimicrobial effects. The incorporation of fluorine enhances the chemical stability and increases its effectiveness against a broad spectrum of pathogenic microorganisms.

The mode of action of Fluorosalan involves the disruption of microbial cell membranes and inhibition of essential enzyme systems within the pathogen, thus preventing their replication and survival. Its efficacy is attributed to its ability to interfere with microbial metabolism and cellular integrity effectively.

Fluorosalan is predominantly employed in clinical settings for the treatment of superficial skin infections and as a preventive measure in surgical procedures to reduce infection rates. The application is typically through topical formulations, enabling direct delivery to the site of infection and minimizing systemic side effects. Due to its potent antibacterial properties and low incidence of resistance, Fluorosalan remains a critical component in infection control protocols.

Formula: C₁₄H₈Br₂F₃NO₂

Purity: Min. 95%

Molecular weight: 439.02 g/mol

Ref: 3D-EAA77606