CAS 477600-74-1

N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Description:

N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, with the CAS number 477600-74-1, is a chemical compound that belongs to the class of pyrrolopyrimidines. This substance features a complex structure characterized by a pyrrolopyrimidine core, which is fused with a piperidine ring. The presence of the N-methyl group and the specific stereochemistry at the piperidine ring (3R,4R) contributes to its unique pharmacological properties. Typically, compounds of this nature are investigated for their potential biological activities, including roles as enzyme inhibitors or receptor modulators. The compound may exhibit solubility in organic solvents and has specific melting and boiling points that are characteristic of its molecular structure. Its synthesis and characterization involve standard organic chemistry techniques, and it may be of interest in medicinal chemistry for developing therapeutic agents. As with many chemical substances, safety data sheets should be consulted for handling and toxicity information.

Formula: C₁₃H₁₉N₅

InChI: InChI=1S/C13H19N5/c1-9-3-5-14-7-11(9)18(2)13-10-4-6-15-12(10)16-8-17-13/h4,6,8-9,11,14H,3,5,7H2,1-2H3,(H,15,16,17)/t9-,11+/m1/s1

InChI key: InChIKey=XRIARWQZLGCQDM-KOLCDFICSA-N

SMILES: N(C)(C1=C2C(NC=C2)=NC=N1)[C@@H]3[C@H](C)CCNC3

Synonyms:

• (3R,4R)-Methyl{(4-methylpiperidin-3-yl)(7H-pyrrolo[2,3-d]pyrimidin-4-yl)}amine
• 1H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-
• N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• n-methyl-n-((3r,4r)-4-methylpiperidin-3-yl)-7h-pyrrolo(2,3-d)pyrimidin-4-amine

1H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-

CAS: 477600-74-1

Formula: C₁₃H₁₉N₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 245.3235

Ref: IN-DA00I8P4

N-Methyl-N-((3R,4R)-4-methylpiperidin-3yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAS: 477600-74-1

Ref: 7W-GX8670

N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-Pyrrolo[2,3-d]Pyrimidin-4-Amine

CAS: 477600-74-1

N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-Pyrrolo[2,3-d]Pyrimidin-4-Amine

Purity: 99%

Molecular weight: 245.32g/mol

Ref: 54-OR1014435

Tofacitinib Impurity 10

CAS: 477600-74-1

Formula: C₁₃H₁₉N₅

Color and Shape: White To Off-White Solid

Molecular weight: 245.33

Ref: 4Z-T-117026

N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Controlled Product

CAS: 477600-74-1

Applications N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a substance used in the identification of related substances in the degradation products of tofacitinib citrate using LC-MS technique for process monitoring and quality assurance. A reagent for the synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor.
References Wu, X., et al.: J. Pharm. Biomed. Anal., 143, 17 (2017); Marican, A., et al.: Tetrahedron Lett., 54, 5096 (2013)

Formula: C₁₃H₁₉N₅

Color and Shape: White

Molecular weight: 245.32

Ref: TR-M296155

Tofacitinib Impurity M

CAS: 477600-74-1

Formula: C₁₃H₁₉N₅

Molecular weight: 245.33

Ref: ST-EA-CP-T23002

N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAS: 477600-74-1

Formula: C₁₃H₁₉N₅

Purity: 98%

Molecular weight: 245.33

Ref: 10-F211899

N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAS: 477600-74-1

Intermediate in the synthesis of tofacitinib

Formula: C₁₃H₁₉N₅

Purity: Min. 95%

Molecular weight: 245.32 g/mol

Ref: 3D-FM154245