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CAS 478182-28-4

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4′-Azidocytidine

Description:
4′-Azidocytidine is a nucleoside analog characterized by the presence of an azido group at the 4' position of the ribose sugar moiety. This modification enhances its potential for incorporation into RNA, making it a subject of interest in various biochemical and pharmaceutical applications, particularly in antiviral research and as a tool in molecular biology. The azido group is known for its reactivity, allowing for click chemistry applications, which can facilitate the labeling and tracking of RNA molecules. In terms of solubility, 4′-Azidocytidine is typically soluble in polar solvents, which is common for nucleosides. Its structure allows it to mimic natural nucleosides, enabling it to participate in nucleic acid synthesis and potentially interfere with viral replication processes. The compound's unique properties make it valuable for studying RNA dynamics and developing therapeutic strategies against RNA viruses. As with many nucleoside analogs, careful consideration of its pharmacokinetics and biological effects is essential for its application in research and medicine.
Formula:C9H12N6O5
InChI:InChI=1S/C9H12N6O5/c10-4-1-2-15(8(19)12-4)7-5(17)6(18)9(3-16,20-7)13-14-11/h1-2,5-7,16-18H,3H2,(H2,10,12,19)/t5-,6+,7-,9-/m1/s1
InChI key:InChIKey=ODLGMSQBFONGNG-JVZYCSMKSA-N
SMILES:N(=[N+]=[N-])[C@]1(CO)O[C@H]([C@H](O)[C@@H]1O)N2C(=O)N=C(N)C=C2
Synonyms:
  • 4'-Azidocytidine
  • 4′-C-Azidocytidine
  • Cytidine, 4′-C-azido-
  • R 1479
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