CAS 478296-72-9

Gabapentin enacarbil

Description:

Gabapentin enacarbil is a prodrug of gabapentin, primarily used for the treatment of neuropathic pain and restless legs syndrome. It is characterized by its ability to enhance the bioavailability of gabapentin, allowing for improved absorption and therapeutic efficacy. The chemical structure of gabapentin enacarbil includes an enacarbil moiety that facilitates its conversion to gabapentin in the body. This compound is typically administered orally and is known for its relatively favorable safety profile, with common side effects including dizziness, fatigue, and somnolence. Gabapentin enacarbil acts by modulating the release of excitatory neurotransmitters, thereby reducing neuronal excitability. Its pharmacokinetics are influenced by factors such as food intake, which can affect absorption rates. Overall, gabapentin enacarbil represents a significant advancement in the management of certain neurological conditions, providing an alternative for patients who may not respond adequately to traditional gabapentin therapy.

Formula: C₁₆H₂₇NO₆

InChI: InChI=1S/C16H27NO6/c1-11(2)14(20)22-12(3)23-15(21)17-10-16(9-13(18)19)7-5-4-6-8-16/h11-12H,4-10H2,1-3H3,(H,17,21)(H,18,19)

InChI key: InChIKey=TZDUHAJSIBHXDL-UHFFFAOYSA-N

SMILES: C(NC(OC(OC(C(C)C)=O)C)=O)C1(CC(O)=O)CCCCC1

Synonyms:

• 1-[[(1-(Isobutanoyloxy)ethoxy)carbonyl]aminomethyl]cyclohex-1-ylacetic acid
• Cyclohexaneacetic acid, 1-[[[[1-(2-methyl-1-oxopropoxy)ethoxy]carbonyl]amino]methyl]-
• Gabapentin enacarbil
• Horizant
• Regnite
• Xp 13512
• 1-[[[[1-(2-Methyl-1-oxopropoxy)ethoxy]carbonyl]amino]methyl]cyclohexaneacetic acid

Gabapentin enacarbil

CAS: 478296-72-9

Formula: C₁₆H₂₇NO₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 329.3887

Ref: IN-DA00D9KS

2-(1-((((1-(Isobutyryloxy)Ethoxy)Carbonyl)Amino)Methyl)Cyclohexyl)Acetic Acid

CAS: 478296-72-9

2-(1-((((1-(Isobutyryloxy)Ethoxy)Carbonyl)Amino)Methyl)Cyclohexyl)Acetic Acid

Purity: 97%

Molecular weight: 329.39g/mol

Ref: 54-OR1026122

Gabapentin Enarcarbil

CAS: 478296-72-9

Formula: C₁₆H₂₇NO₆

Molecular weight: 329.40

Ref: 4Z-G-1011

Gabapentin enacarbil

CAS: 478296-72-9

Gabapentin enacarbil (XP-13512) is a prodrug for the anticonvulsant and analgesic gabapentin, offering sustained dose-proportional exposure and predictable bioavailability.

Formula: C₁₆H₂₇NO₆

Purity: 99.31%

Color and Shape: Solid

Molecular weight: 329.39

Ref: TM-T15366

GABAPENTIN ENACARBIL

CAS: 478296-72-9

Formula: C₁₆H₂₇NO₆

Purity: 95.0%

Molecular weight: 329.393

Ref: 10-F512708

Gabapentin Enacarbil-d6 Sodium Salt

Controlled Product

CAS: 478296-72-9, 912486-72-7

Formula: C₁₆D₆H₂₁NO₆

Color and Shape: Neat

Molecular weight: 335.426

Ref: TR-G117242

Gabapentin enacarbil

Controlled Product

CAS: 478296-72-9

Prodrug of Gabapentin

Formula: C₁₆H₂₇NO₆

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 329.39 g/mol

Ref: 3D-FG31551