CAS 478336-92-4

5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl ester

Description:

5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl ester, identified by CAS number 478336-92-4, is a chemical compound characterized by its isoxazole ring structure, which contributes to its unique reactivity and biological properties. This compound features a methyl ester functional group, enhancing its solubility and potential bioavailability. The presence of a 4-hydroxyphenyl group suggests that it may exhibit phenolic characteristics, possibly influencing its antioxidant activity and interactions with biological systems. The dihydro configuration indicates that the compound has a saturated portion, which may affect its stability and reactivity compared to fully unsaturated analogs. Overall, this compound may be of interest in medicinal chemistry and pharmacology, particularly for its potential therapeutic applications, although specific biological activities and mechanisms would require further investigation. As with many chemical substances, safety data and handling precautions should be considered when working with this compound in laboratory settings.

Formula: C₁₂H₁₃NO₄

MIF Antagonist, ISO-1

CAS: 478336-92-4

Formula: C₁₂H₁₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.2359

Ref: IN-DA00DB6E

Methyl 2-(3-(4-Hydroxyphenyl)-4,5-Dihydroisoxazol-5-Yl)Acetate

CAS: 478336-92-4

Methyl 2-(3-(4-Hydroxyphenyl)-4,5-Dihydroisoxazol-5-Yl)Acetate

Purity: 99%

Molecular weight: 235.24g/mol

Ref: 54-OR1023809

ISO-1

CAS: 478336-92-4

ISO-1

Purity: ≥98%

Molecular weight: 235.24g/mol

Ref: 54-BUP13087

ISO-1

CAS: 478336-92-4

Formula: C₁₂H₁₃NO₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 235.24

Ref: 3B-I1119

ISO-1

CAS: 478336-92-4

ISO-1 (MIF Antagonist) is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-κB/TNF-α secretion from LPS-treated macrophages.

Formula: C₁₂H₁₃NO₄

Purity: 98.06% - 98.65%

Color and Shape: Solid

Molecular weight: 235.24

Ref: TM-T3680

Methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate

CAS: 478336-92-4

Formula: C₁₂H₁₃NO₄

Purity: 98%

Molecular weight: 235.239

Ref: 10-F244654

MIF Antagonist, ISO-1

CAS: 478336-92-4

ISO-1 is a novel MIF antagonist that has been shown to inhibit the activation of WST-1. ISO-1 is currently being studied for its effects on autoimmune diseases, cancer and bowel disease. ISO-1 blocks the chemoattractant protein CXCL12, which is used to recruit white blood cells to the site of inflammation. It also inhibits enzymes that are involved in oxidative stress and inflammation, such as LOX and COX2. ISO-1 has been shown to inhibit the production of growth factor β1, which is responsible for stimulating cell proliferation. This drug has been tested in an experimental model for epithelial mesenchymal transition (EMT) and found to have therapeutic potential in bowel disease.

Formula: C₁₂H₁₃NO₄

Purity: Min. 95%

Molecular weight: 235.24 g/mol

Ref: 3D-DUA33692