Cytidine-2'-13C (9CI) is a stable isotope-labeled form of cytidine, a nucleoside composed of a pyrimidine base (cytosine) and a ribose sugar. The designation "2'-13C" indicates that the carbon atom at the 2' position of the ribose sugar is replaced with the carbon-13 isotope, which is a non-radioactive isotope of carbon. This modification allows for the use of cytidine-2'-13C in various biochemical and metabolic studies, particularly in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry, where it can help trace metabolic pathways and study nucleic acid metabolism. The compound retains the essential characteristics of cytidine, including its role in RNA synthesis and its involvement in cellular processes. As a chemical entity, it is typically soluble in water and exhibits stability under physiological conditions. The CAS number 478511-19-2 uniquely identifies this specific isotope-labeled compound, facilitating its use in research and applications in biochemistry and molecular biology.

Cytidine-2'-13C (9CI)

478511-19-2: Cytidine-2'-13C (9CI) is a stable isotope-labeled form of cytidine, a nucleoside composed of a pyrimidine base (cytosine) and a ribose sugar. The designation "2'-13C" indicates that the carbon atom at the 2' position of the ribose sugar is replaced with the carbon-13 isotope, which is a non-radioactive isotope of carbon. This modification allows for the use of cytidine-2'-13C in various biochemical and metabolic studies, particularly in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry, where it can help trace metabolic pathways and study nucleic acid metabolism. The compound retains the essential characteristics of cytidine, including its role in RNA synthesis and its involvement in cellular processes. As a chemical entity, it is typically soluble in water and exhibits stability under physiological conditions. The CAS number 478511-19-2 uniquely identifies this specific isotope-labeled compound, facilitating its use in research and applications in biochemistry and molecular biology.

<p>2'-13CCytidine is a cytidine nucleoside that inhibits the synthesis of RNA and DNA in cells. It is an analog of cytarabine, which is a pyrimidine nucleoside and an antineoplastic agent. 2'-13CCytidine has been shown to be effective as an antiviral agent against HIV-1 and HSV-2, as well as an immunosuppressant for the treatment of autoimmune diseases such as rheumatoid arthritis. This drug is used in chemotherapy to inhibit cell division in leukemia.</p>

CAS 478511-19-2

Cytidine-2'-13C (9CI)

2'-13CCytidine

Ref: 3D-NC34302