CAS 478644-12-1

GW 813893

Description:

GW 813893, with the CAS number 478644-12-1, is a chemical compound that has garnered attention in pharmacological research, particularly in the context of its potential therapeutic applications. It is classified as a selective agonist of the peroxisome proliferator-activated receptor gamma (PPAR-γ), which plays a crucial role in regulating glucose metabolism and lipid storage. This compound is often studied for its implications in treating metabolic disorders, including type 2 diabetes and obesity. GW 813893 exhibits a high affinity for PPAR-γ, leading to the activation of pathways that enhance insulin sensitivity and promote adipogenesis. Its chemical structure includes specific functional groups that contribute to its biological activity and selectivity. As with many research compounds, the safety profile, pharmacokinetics, and long-term effects of GW 813893 are subjects of ongoing investigation, making it a compound of interest in the field of medicinal chemistry and drug development.

Formula: C₁₇H₂₂ClN₃O₅S₂

Synonyms:

• GSK-813893
• GW 813893
• GSK 813893
• Ethenesulfonamide, 2-(5-chloro-2-thienyl)-N-[(3S)-1-[(1S)-1-methyl-2-(4-morpholinyl)-2-oxoethyl]-2-oxo-3-pyrrolidinyl]-, (1E)-
• (E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-morpholin-4-yl-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]ethenesulfonamide
• GSK813893

GW-813893

CAS: 478644-12-1

GW-813893: potent, selective oral factor Xa inhibitor; Ki 4.0 nM (FXa), 9.7 nM (prothrombinase).

Formula: C₁₇H₂₂ClN₃O₅S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 447.96

Ref: TM-T27514