CAS 479-13-0

Coumestrol

Description:

Coumestrol is a naturally occurring phytoestrogen, classified as a coumestan, which is a type of flavonoid. It is primarily found in various legumes, particularly in alfalfa and clover. Coumestrol exhibits estrogenic activity, meaning it can bind to estrogen receptors and mimic the effects of estrogen in the body, which has implications for both plant biology and potential health effects in humans. The chemical structure of coumestrol features a fused benzopyran ring system, contributing to its biological activity. It is often studied for its potential role in modulating hormonal activity and its effects on reproductive health. Additionally, coumestrol has been investigated for its antioxidant properties and potential protective effects against certain diseases. Its solubility characteristics typically indicate that it is more soluble in organic solvents than in water, which influences its bioavailability and interaction within biological systems. Overall, coumestrol represents an interesting compound in both nutritional science and pharmacology due to its diverse biological activities.

Formula: C₁₅H₈O₅

InChI: InChI=1S/C15H8O5/c16-7-1-3-9-11(5-7)19-14-10-4-2-8(17)6-12(10)20-15(18)13(9)14/h1-6,16-17H

InChI key: InChIKey=ZZIALNLLNHEQPJ-UHFFFAOYSA-N

SMILES: O=C1C2=C(C=3C(O1)=CC(O)=CC3)OC=4C2=CC=C(O)C4

Synonyms:

• 2-(2,4-Dihydroxyphenyl)-6-hydroxy-3-benzofurancarboxylic acid δ-lactone
• 3,9-Dihydroxy-6H-benzofuro(3,2-c)(1)benzopyran-6-one
• 3,9-Dihydroxy-[1]benzofuro[3,2-c]chromen-6-one
• 3,9-dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one
• 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, delta-lactone (6CI)
• 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, δ-lactone
• 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 3,9-dihydroxy-
• Brn 0266702
• Ccris 7311
• Coumesterol
• Cumoesterol
• Cumoestrol
• Cumostrol
• Nsc 22842

Coumestrol

CAS: 479-13-0

Coumestrol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₅H₈O₅

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 268.23

Ref: 11-0557S

3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one

CAS: 479-13-0

Formula: C₁₅H₈O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 268.2210

Ref: IN-DA003IR8

Coumestrol

CAS: 479-13-0

Formula: C₁₅H₈O₅

Molecular weight: 268.22

Ref: 7W-GP2937

Coumestrol

CAS: 479-13-0

Coumestrol

Purity: ≥95%

Molecular weight: 268.22g/mol

Ref: 54-BUP01465

Coumestrol

CAS: 479-13-0

Formula: C₁₅H₈O₅

Purity: 95%~99%

Molecular weight: 268.224

Ref: BP-SBP02765

Coumestrol

CAS: 479-13-0

Coumestrol in soybeans inhibits ES2 cell growth (IC50: 50 μM) and combats neurological issues, cancer, and autoimmunity.

Formula: C₁₅H₈O₅

Purity: 96.23% - 99.23%

Color and Shape: Solid

Molecular weight: 268.22

Ref: TM-TQ0295

Coumestrol

CAS: 479-13-0

Lactone

Formula: C₁₅H₈O₅

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 268.22

Ref: 5G-82308

Coumestrol

Controlled Product

CAS: 479-13-0

Applications This compound has estrogenic activity. It exhibits bright blue fluorescence in neutral or acid solution, and greenish-yellow fluorescence in strong alkali solution.
References Wolfbeis, O.S. & K. Schaffner: Photochem. Photobiol., 32, 143(1980), Bickoff et al.: J.Am. Chem Soc. 80, 3969 (1958)

Formula: C₁₅H₈O₅

Color and Shape: Neat

Molecular weight: 268.22

Ref: TR-C781000

Coumestrol

CAS: 479-13-0

Coumestrol is a phytoestrogen compound, which is a naturally occurring compound found in a variety of plants, such as soybeans, clover, and alfalfa. It is derived from the metabolic processes within these plants. Coumestrol exhibits estrogenic activity, acting as an agonist for estrogen receptors. This biological activity enables coumestrol to mimic the action of endogenous estrogens, thereby influencing estrogen-responsive pathways.

Formula: C₁₅H₈O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 268.22 g/mol

Ref: 3D-FC20578